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Effects of Oral Glutathione Precursors’ Supplementation on Human Glutathione Level

  • Conference paper
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2nd International Conference for Innovation in Biomedical Engineering and Life Sciences (ICIBEL 2017)

Part of the book series: IFMBE Proceedings ((IFMBE,volume 67))

Abstract

Glutathione (GSH) is a tripeptide of cysteine, glutamate, and glycine. These amino acids made the synthesis of GSH possible and act as a major cellular antioxidant in the body. The production of GSH in the body depends on several factors; such as dietary intake and cysteine availability. With the turnover rate of endogenous GSH can be as high as 65% per day, more consumers has turned to GSH supplement to maintain or boost up their GSH level. GSH supplement available in the market usually contains GSH precursor/s that are said to be able to increase GSH level in the body. In this study, the oral GSH supplement used contains all three precursors of GSH; cystine replacing cysteine, glutamate, and glycine. Subjects were asked to consume the supplement according to the instructed dosage in order to measure the effects of oral GSH precursors’ supplement on human GSH level after the three-month study period ends. The results from this study suggest that the oral GSH precursors’ supplement increases GSH level across the test groups after the three-month study period.

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Acknowledgements

This research was supported and funded by Chakra We Care Resources Sdn Bhd, Project No. PV004-2017.

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Authors and Affiliations

  1. Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia

    Asdani Saifullah Dolbashid, Mas Sahidayana Mohktar, Wan Safwani Wan Kamarul Zaman, Nur Rasyidah Hasan Basri, Mohd Faiz Azmi & Sakunie Sawai

  2. Faculty of Engineering, Center for Innovation in Medical Engineering, University of Malaya, Kuala Lumpur, Malaysia

    Mas Sahidayana Mohktar & Wan Safwani Wan Kamarul Zaman

  3. Chakra We Care Resources Sdn Bhd, Petaling Jaya, Selangor, Malaysia

    Mohd Yusof Hasif Ilyasa

Authors
  1. Asdani Saifullah Dolbashid
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  2. Mas Sahidayana Mohktar
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  4. Nur Rasyidah Hasan Basri
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Correspondence to Mas Sahidayana Mohktar .

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Editors and Affiliations

  1. Department of Biomedical Engineering, Faculty of Engineering, Centre for Innovation in Medical Engineering, University of Malaya, Kuala Lumpur, Malaysia

    Fatimah Ibrahim

  2. Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia

    Juliana Usman

  3. Department of Biomedical Engineering, Faculty of Engineering, Centre for Innovation in Medical Engineering, University of Malaya, Kuala Lumpur, Malaysia

    Mohd Yazed Ahmad

  4. Department of Rehabilitation Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

    Norhamizan Hamzah

  5. Department of Biomedical Engineering, Faculty of Engineering, Centre for Innovation in Medical Engineering, University of Malaya, Kuala Lumpur, Malaysia

    Swe Jyan Teh

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Dolbashid, A.S. et al. (2018). Effects of Oral Glutathione Precursors’ Supplementation on Human Glutathione Level. In: Ibrahim, F., Usman, J., Ahmad, M., Hamzah, N., Teh, S. (eds) 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences. ICIBEL 2017. IFMBE Proceedings, vol 67. Springer, Singapore. https://doi.org/10.1007/978-981-10-7554-4_26

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  • DOI: https://doi.org/10.1007/978-981-10-7554-4_26

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-7553-7

  • Online ISBN: 978-981-10-7554-4

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