Biochemistry of the Host Pathogen Interaction
Biochemical studies on the growth and survival of a pathogen and the changes it induces in its host can ultimately lead to a better understanding of the disease development, its epidemiology, and its control. Ideal prerequisites for meaningful studies of the biochemistry of the host-parasite interaction are (a) a clear understanding of the genetic control of virulence and avirulence in the parasite and of susceptibility and resistance in the host, (b) precise histological and cytological descriptions of spore germination and infection and the establishment and development of the host-pathogen interaction, and (c) the availability of methods for maintaining the pathogen alone and in combinations with its host, under controlled conditions. Unfortunately, these criteria have not yet been satisfactorily met for downy mildew of crucifers. The biosynthesis of the defence-related compounds like camalexin, salicylic acid, and lignin in Arabidopsis provides resistance to crucifers against downy mildew pathogen.
- Glazebrook J, Zook M, Mert F, Kagan I, Rogers ER, Crute IR, Holub EB, Hammerschmidt R, Ausubel FM (1997) Phytoalexin deficient mutants of Arabidopsis reveal that PAD4 encodes a regulatory factor and that four PAD genes contribute to downy mildew resistance. Genetics 146:381–392PubMedPubMedCentralGoogle Scholar
- Mauch-Mani B, Croft KPC, Slusarenko AJ (1993) The genetic basis of resistance of Arabidopsis thaliana L. Heyhn. to Peronospora parasitica. In: Davis KR, Hammerschmidt R (eds) Arabidopsis thaliana as a model for plant–pathogen interactions. APS Press, St Paul, pp 5–20Google Scholar
- Ride JP (1983) Cell walls and other structural barriers in defence. In: Callow JA (ed) Biochemical plant pathology. Wiley, Chichester, pp 215–236Google Scholar
- Singh SB, Singh DV, Bais BS (1980) In vivo cellulase and pectinase production by Albugo candida and Peronospora parasitica. Indian Phytopathol 33:370–371Google Scholar
- Slusarenko AJ, Mauch-Mani B (1991) Downy mildew of Arabidopsis thaliana caused by Peronospora parasitica: a model system for the investigation of the molecular biology of host-pathogen interactions. In: Hennecke H (ed) Advances in the molecular genetics of plant–microbe interactions, vol 1. Kluwer Academic Press, Dordrecht, pp 280–283CrossRefGoogle Scholar