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Manno-oligosaccharides as Prebiotic-Valued Products from Agro-waste

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Book cover Biosynthetic Technology and Environmental Challenges

Part of the book series: Energy, Environment, and Sustainability ((ENENSU))

Abstract

Agriculture is the backbone of Indian economy, is carried out for primary products where a significant amount of agro-waste is produced. About 72% of fruits and vegetable production in India goes waste, due to their processing variability which meets about 1.4% of the total global trade. Therefore, the agro-waste utilization for human benefit is the major concern for environmental sustainability. Such waste can be effectively used for the production of useful compounds for animals and human beings. Lignocellulosic agro-waste has been explored for the production of energy as biofuels. Such biomass can also be considered to be useful for the production of prebiotic oligosaccharides. Different agro-wastes such as copra meal, potato peel, rice straw, wheat straw, corncob, palm kernel meal, etc., can be used for the production of different oligosaccharides. Oligosaccharides are short chains of monosaccharides of the size ranging from two to ten units of monosaccharides or simple sugars. The oligosaccharides are highly stable and are used as dietary supplement possessing prebiotic, antioxidant activity and potential immune-modulating properties. Manno-oligosaccharides can be produced from pretreated agro-waste by hydrolysis with endo-β-(1 → 4)-mannanase. MOSs has significant stability against α-amylase, intestinal juice, and simulated gastric juice which is an essential parameter for oligosaccharides to serve as a prebiotic. Nevertheless, MOSs also supports higher growth rate of probiotic bacteria Bifidobacterium infantis and Lactobacillus acidophilus as compared to commercial prebiotic. In addition to prebiotic properties, MOS significantly reduces the growth of colon cancer cells that depicts their antagonistic properties without any cytotoxic effect against the normal cell culture. This chapter will describe the roles of manno-oligosaccharides recovered from agro-waste which have applications as prebiotics, acting antagonistic agent against cancer cells and as anti-allergic agents.

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References

  • Adrizal A, Yusrizal Y, Fakhri S, Haris W, Ali E, Angel CR (2011) Feeding native laying hens diets containing palm kernel meal with or without enzyme supplementations: 1. Feed conversion ratio and egg production. The. Journal of Applied Poultry Research 20(1):40–49

    Article  Google Scholar 

  • Al-Assaf S, Phillips GO, Williams PA (2006) Characterization and properties of Acacia senegal (l.) willd. var. senegal with enhanced properties (Acacia (sen) super gum(tm)): part 1-controlled maturation of Acacia senegal var. senegal to increase viscoelasticity, produce a hydrogel form and convert a poor into a good emulsifier. Food Hydrocolloids 20:369–377

    Article  Google Scholar 

  • Alves EF, Bose SK, Francis RC, Colodette JL, Iakovlev M, Van Heiningen A (2010) Carbohydrate composition of eucalyptus, bagasse and bamboo by a combination of methods. Carbohyd Polym 82(4):1097–1101

    Article  Google Scholar 

  • Barfod AS, Bergmann B, Pedersen HB (1990) The vegetable ivory industry: surviving and doing well in Ecuador. Econ Bot 44(3):293–300

    Article  Google Scholar 

  • Bartnicki-Garcia S (1968) Cell wall chemistry, morphogenesis, and taxonomy of fungi. Annual Reviews in Microbiology 22(1):87–108

    Article  Google Scholar 

  • Blibech M, Chaari F, Bhiri F, Dammak I, Ghorbel RE, Chaabouni SE (2011) Production of manno-oligosaccharides from locust bean gum using immobilized Penicillium occitanis mannanase. J Mol Catal B Enzym 73(1):111–115

    Google Scholar 

  • Camire ME, Violette D, Dougherty MP, McLaughlin MA (1997) Potato peel dietary fiber composition: effects of peeling and extrusion cooking processes. Journal Agriculture and Food Chemistry 45:1404–1408

    Article  Google Scholar 

  • Campos-Vega R, Loarca-Piña G, Vergara-Castañeda HA, Oomah BD (2015) Spent coffee grounds: A review on current research and future prospects. Trends Food Sci Technol 45(1):24–36

    Article  Google Scholar 

  • Carvalheiro F, Esteves MP, Parajó JC, Pereira H, Gírio FM (2004) Production of oligosaccharides by autohydrolysis of brewery’s spent grain. Bioresource Technology 91(1), 93–100

    Google Scholar 

  • Conway PL (1995) Microbial ecology of the human large intestine. In Human Colonic Bacteria: Role in Nutrition, Physiology and Pathology, [GR Gibson and GT Macfarlane, editors]. Boca Raton, FL: CRC Press, 1–24

    Google Scholar 

  • Cui SW, Wang Q (2009) Cell wall polysaccharides in cereals: chemical structures and functional properties. Struct Chem 20(2):291–297

    Article  Google Scholar 

  • Denev SA (2006) Role of Lactobacilli Gastrointestinal Ecosystem. Bulgarian Journal of Agricultural Science 12(1):63

    Google Scholar 

  • Dias LG, Veloso ACA, Correia DM, Rocha O, Torres D, Rocha I (2009) UV spectrophotometry method for the monitoring of galacto-oligosaccharides production. Food Chem 113(1):246–252

    Article  Google Scholar 

  • Eslyn WE, Kirk TK, Effland MJ (1975) Changes in the chemical composition of wood caused by six soft-rot fungi. Phytopathology 65(4):473–476

    Article  Google Scholar 

  • Fernández J, Redondo-Blanco S, Miguélez EM, Villar CJ, Clemente A, Lombó F (2015) Healthy effects of prebiotics and their metabolites against intestinal diseases and colorectal cancer. Microbiology 1(1):48–71

    Google Scholar 

  • Freter R, Jones G (1976) Adhesive properties of Vibrio cholera: Nature of the interaction with mucosal surfaces. Infect Immun 14:246–256

    Google Scholar 

  • Fukasawa T, Murashima K, Matsumoto I, Hosono A, Ohara H, Nojiri C, Koga J, Kubota H, Kanegae M, Kaminogawa S, Abe K, Kono T (2007) Identification of marker genes for intestinal immune-modulating effect of a fructo-oligosaccharide by DNA microarray analysis. J Agric Food Chem 55:3174–3179

    Article  Google Scholar 

  • Ganter JLMS, Heyraud A, Petkowicz O, Rinaudo M, Reicher F (1995) Galactomannans from Brazilian seeds: characterization of the oligosaccharides produced by mild acid hydrolysis. International Journal of Biological Macromolecule 17:13–19

    Article  Google Scholar 

  • Ghosh A, Luís AS, Brás JL, Fontes CM, Goyal A (2013) Thermostable recombinant β-(1 → 4)-mannanase from C. thermocellum: biochemical characterization and manno-oligosaccharides production. J Agric Food Chem 61(50):12333–12344

    Article  Google Scholar 

  • Ghosh A, Verma AK, Tingirikari JR, Shukla R, Goyal A (2015) Recovery and purification of oligosaccharides from copra meal by recombinant endo-β-mannanase and deciphering molecular mechanism involved and its role as potent therapeutic agent. Mol Biotechnol 57(2):111–127

    Article  Google Scholar 

  • Gibson GR, Beaumont A (1996) An overview of human colonic bacteriology in health and disease. In Gut Flora and Health—Past, Present and Future. International Congress and Symposium [AR Leeds and IR Rowland, editors]. London: The Royal Society of Medicine Press Ltd, 219, 3–11

    Google Scholar 

  • Gibson GR, Ottaway PB, Rastall RA (2000) Prebiotics: new developments in functional foods. Chandos Publishing, Oxford, UK

    Book  Google Scholar 

  • Gibson GR, Roberfroid MB (1995) Dietary modulation of the human colonic microbiota: Introducing the concept of prebiotics. The Journal of Nutrition 125(6):1401

    Google Scholar 

  • Gomes AM, Malcata FX (1999) Bifidobacterium spp. and Lactobacillus acidophilus: biological, biochemical, technological and therapeutical properties relevant for use as probiotics. Trends Food Sci Technol 10(4):139–157

    Article  Google Scholar 

  • Hossain MZ, Abe JI, Hizukuri S (1996) Multiple forms of β-mannanase from Bacillus sp. KK01. Enzyme and Microbial Technology 18(2):95–98

    Article  Google Scholar 

  • Jian HL, Zhu LW, Zhang WM, Sun DF, Jiang JX (2013) Enzymatic production and characterization of manno-oligosaccharides from Gleditsia sinensis galactomannan gum. Int J Biol Macromol 55:282–288

    Article  Google Scholar 

  • Jooste T, García-Aparicio MP, Brienzo M, Van Zyl WH, Görgens JF (2013) Enzymatic hydrolysis of spent coffee ground. Appl Biochem Biotechnol 169(8):2248–2262

    Article  Google Scholar 

  • Katsuraya K, Okuyama K, Hatanaka Oshima R, Sato T, Matsuzaki K (2003) Constitution of konjac glucomannan: chemical analysis and 13C NMR spectroscopy. Carbohyd Polym 53(2):183–189

    Article  Google Scholar 

  • Klaenhammer TR (1988) Bacteriocins of lactic acid bacteria. Biochimie 70(3):337–349

    Article  Google Scholar 

  • Klaenhammer TR (1993) Genetics of bacteriocins produced by lactic acid bacteria. FEMS Microbiol Rev 12(3):39–85

    Article  Google Scholar 

  • Kurakake M, Sumida T, Masuda D, Oonishi S, Komaki T (2006) Production of galacto-manno-oligosaccharides from guar gum by β-mannanase from Penicillium oxalicum SO. J Agric Food Chem 54(20):7885–7889

    Article  Google Scholar 

  • Liang S, McDonald AG (2014) Chemical and thermal characterization of potato peel waste and its fermentation residue as potential resources for biofuel and bioproducts production. J Agric Food Chem 62(33):8421–8429

    Article  Google Scholar 

  • Liu HT, He JL, Li WM, Yang Z, Wang YX, Bai XF, Du YG (2010) Chitosan oligosaccharides protect human umbilical vein endothelial cells from hydrogen peroxide-induced apoptosis. Carbohyd Polym 80(4):1062–1071

    Article  Google Scholar 

  • Madurwar MV, Ralegaonkar RV, Mandavgane SA (2013) Application of agro-waste for sustainable construction materials: A review. Constr Build Mater 38:872–878

    Article  Google Scholar 

  • Maeda M, Shimahara H, Sugiyama N (1980) Detailed examination of the branched structure of konjac glucomannan. Agric Biol Chem 44(2):245–252

    Google Scholar 

  • Maru V, Hewale S, Mantri H, Ranade V (2015) Partial purification and characterization of mannan oligosaccharides from cell wall of Saccharomyces cerevisiae. International Journal of Current Microbiology and Applied Sciences 4(12):705–711

    Google Scholar 

  • Moreira LRS (2008) An overview of mannan structure and mannan-degrading enzyme systems. Appl Microbiol Biotechnol 79(2):165

    Article  Google Scholar 

  • Mussatto SI, Carneiro LM, Silva J, Roberto IC, Teixeira JA (2011) A study on chemical constituents and sugars extraction from spent coffee grounds. Carbohyd Polym 83(2):368–374

    Article  Google Scholar 

  • Mussatto SI, Mancilha IM (2007) Non-digestible oligosaccharides: a review. Carbohyd Polym 68(3):587–597

    Article  Google Scholar 

  • Öhgren K, Bura R, Saddler J, Zacchi G (2007) Effect of hemicellulose and lignin removal on enzymatic hydrolysis of steam pretreated corn stover. Biores Technol 98(13):2503–2510

    Article  Google Scholar 

  • Ojima T (2013) Polysaccharide-degrading enzyme from herbivorous marine invertebrates. Marine Enzymes for Biocatalysis, [Antonio Trincone editor] Woodhead, 13(38), 333–360

    Google Scholar 

  • Ong LGA, Abd-Aziz S, Noraini S, Karim MIA, Hassan MA (2004) Enzyme production and profile by Aspergillus niger during solid substrate fermentation using palm kernel cake as substrate. Appl Biochem Biotechnol 118(1–3):73–79

    Article  Google Scholar 

  • Otieno DO, Ahring BK (2012) The potential for oligosaccharide production from the hemicellulose fraction of biomasses through pretreatment processes: xylooligosaccharides (XOS), arabinooligosaccharides (AOS), and manno-oligosaccharides (MOS). Carbohyd Res 360:84–92

    Article  Google Scholar 

  • Oyofo BA, Droleskey RE, Norman JO, Mollenhauer HH, Ziprin RL, Corrier DE, DeLoach JR (1989) Inhibition by mannose of in vitro colonization of chicken small intestine by Salmonella typhimurium. Poult Sci 68(10):1351–1356

    Article  Google Scholar 

  • Ozaki K, Fujii S, Hayashi M (2007) Effect of dietary manno-oligosaccharides on immune system of ovalalbumin sensitized mice. J Health Sci 53(6):766–770

    Article  Google Scholar 

  • Pappu A, Saxena M, Asolekar SR (2007) Solid wastes generation in India and their recycling potential in building materials. Build Environ 42(6):2311–2320

    Article  Google Scholar 

  • Patel S, Goyal A (2011) Functional oligosaccharides: production, properties and applications. World J Microbiol Biotechnol 27(5):1119–1128

    Article  Google Scholar 

  • Prawitwon P, Takigami S, Phillips GO (2007) Effects of γ-irradiation on molar mass and properties of Konjac mannan. Food Hydrocolloids 21:1362–1367

    Article  Google Scholar 

  • Qiang X, YongLie C, QianBing W (2009) Health benefit application of functional oligosaccharides. Carbohyd Polym 77(3):435–441

    Article  Google Scholar 

  • Rahmani N, Kashiwagi N, Lee J, Niimi-Nakamura S, Matsumoto H, Kahar P, Kondo A (2017) Mannan endo-β-1,4 mannosidase from Kitasatospora sp. isolated in Indonesia and its potential for production of manno-oligosaccharides from mannan polymers. Applied and Industrial Microbiology and Biotechnology Express, 7(1), 100

    Google Scholar 

  • Ramanathan A, Parthasarathy R (2014) Fruit wastages from farm gate to retail outlets in Tamil Nadu, India-with specific focus on fruit processing units. Middle-East Journal of Scientific Research 21:1994–2003

    Google Scholar 

  • Raval MY (2014) Alternative of conventional solid fuels: Renewable Energy from Fields. International Journal of Engineering and Technical Research 2(7):15–20

    Google Scholar 

  • Rezaei S, Faseleh Jahromi M, Liang JB, Zulkifli I, Farjam AS, Laudadio V, Tufarelli V (2015) Effect of oligosaccharides extract from palm kernel expeller on growth performance, gut microbiota and immune response in broiler chickens. Poult Sci 94(10):2414–2420

    Article  Google Scholar 

  • Rivière A, Selak M, Lantin D, Leroy F, De Vuyst, L (2016) Bifidobacteria and butyrate-producing colon Bacteria: Importance and strategies for their stimulation in the human gut. Frontiers in Microbiology, 7, PMC4923077

    Google Scholar 

  • Roberfroid M, Slavin J (2000) Non-digestible oligosaccharides. Crit Rev Food Sci Nutr 40(6):461–480

    Article  Google Scholar 

  • Rolfe RD (2000) The role of probiotic cultures in the control of gastrointestinal health. The Journal of Nutrition 130(2):396S–402S

    Google Scholar 

  • Rose DJ, Inglett GE (2010) Two-stage hydrothermal processing of wheat (Triticum aestivum) bran for the production of feruloylated arabino-xylooligosaccharides. Agricultural and Food Chemistry 589(10):6427–6432

    Article  Google Scholar 

  • Saittagaroon S, Kawakishi S, Namiki M (1983) Characterization of polysaccharides of copra meal. J Sci Food Agric 34(8):855–860

    Article  Google Scholar 

  • Salvachúa D, Prieto A, López-Abelairas M, Lu-Chau T, Martínez ÁT, Martínez MJ (2011) Fungal pretreatment: an alternative in second-generation ethanol from wheat straw. Biores Technol 102(16):7500–7506

    Article  Google Scholar 

  • Schröder R, Atkinson RG, Redgwell RJ (2009) Re-interpreting the role of endo-β-mannanases as mannan endo transglycosylase/hydrolases in the plant cell wall. Ann Bot 104(2):197–204

    Article  Google Scholar 

  • Shaharuddin S, Razak A, Izwan S, Muhamad II (2014) Sugarcane Bagasse as the potential agro-waste resource for the immobilization of Lactobacillus rhamnosus NRRL 442. Adv Mater Res 1043:214–218

    Article  Google Scholar 

  • Singh V, Tiwari A (2009) Hydrolytic fragmentation of seed gums under microwave irradiation. Int J Biol Macromol 44(2):186–189

    Article  Google Scholar 

  • Srivastava M, Kapoor VP (2005) Seed galactomannans: an overview. Chem Biodivers 2(3):295–317

    Article  Google Scholar 

  • Srivastava PK, Panwar D, Prashanth KH, Kapoor M (2017) Structural characterization and in vitro fermentation of β-manno-oligosaccharides produced from Locust bean gum by GH26 endo-β-1, 4-mannanase (ManB-1601). J Agric Food Chem 65(13):2827–2838

    Article  Google Scholar 

  • Suryawati L, Wilkins MR, Bellmer DD, Huhnke RL, Maness NO, Banat IM (2009) Effect of hydro-thermolysis process conditions on pretreated switch grass composition and ethanol yield by SSF with Kluyveromyces marxianus IMB4. Process Biochem 44(5):540–545

    Article  Google Scholar 

  • Tannock GW (1999) A fresh look at the intestinal microflora. Probiotics: A Critical Review, Wymondham. Horizon Scientific Press, Norfolk, pp 5–14

    Google Scholar 

  • Tilman D, Cassman KG, Matson PA, Naylor R, Polasky S (2002) Agricultural sustainability and intensive production practices. Nature 418(6898):671–677

    Google Scholar 

  • Titapoka S, Keawsompong S, Haltrich D, Nitisinprasert S (2008) Selection and characterization of mannanase-producing bacteria useful for the formation of prebiotic manno-oligosaccharides from copra meal. World J Microbiol Biotechnol 24(8):1425–1433

    Google Scholar 

  • Tokimoto T, Kawasaki N, Nakamura T, Akutagawa J, Tanada S (2005) Removal of lead ions in drinking water by coffee grounds as vegetable biomass. J Colloid Interface Sci 281(1):56–61

    Google Scholar 

  • Tremaroli V, Bäckhed F (2012) Functional interactions between the gut microbiota and host metabolism. Nature 489(7415):242–249

    Article  Google Scholar 

  • Utami W, Meryandini A, Wiryawan KG (2014) Characterization of bacterial mannanase for hydrolyzing palm kernel cake to produce manno-oligosaccharides prebiotics. Media Peternakan 36(3):192–196

    Article  Google Scholar 

  • Walter J (2008) Ecological role of Lactobacilli in the gastrointestinal tract: implications for fundamental and biomedical research. Appl Environ Microbiol 74(16):4985–4996

    Article  Google Scholar 

  • Weijers CA, Franssen MC, Visser GM (2008) Glycosyltransferase-catalyzed synthesis of bioactive oligosaccharides. Biotechnol Adv 26(5):436–456

    Article  Google Scholar 

  • Willför S, Sundberg K, Tenkanen M, Holmbom B (2008) Spruce-derived mannans –A potential raw material for hydrocolloids and novel advanced natural materials. Carbohyd Polym 72(2):197–210

    Article  Google Scholar 

  • Wollowski I, Rechkemmer G, Pool-Zobel BL (2001) Protective role of probiotics and prebiotics in colon cancer. The American Journal of Clinical Nutrition 73(2):451s–455s

    Google Scholar 

  • Wyman CE, Dale BE, Elander RT, Holtzapple M, Ladisch MR, Lee YY, Saddler JN (2009) Comparative sugar recovery and fermentation data following pretreatment of poplar wood by leading technologies. Biotechnol Prog 25(2):333–339

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Biosciences and Bioengineering, Indian Institute of Technology, Guwahati, 781039, Assam, India

    Shweta Singh & Arun Goyal

  2. Department of Botany, Gauhati University, Guwahati, 781014, Assam, India

    Arabinda Ghosh

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  1. Shweta Singh
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  2. Arabinda Ghosh
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  3. Arun Goyal
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Correspondence to Arun Goyal .

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Editors and Affiliations

  1. Gujarat Pollution Control Board, Gandhinagar, Gujarat, India

    Sunita J. Varjani

  2. Microbial Processes and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, Kerala, India

    Binod Parameswaran

  3. Solid and Hazardous Waste Management Division, CSIR-NEERI, Nagpur, Maharashtra, India

    Sunil Kumar

  4. Department of Chemistry, Indian Institute of Technology Delhi, New Delhi, Delhi, India

    Sunil K. Khare

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Singh, S., Ghosh, A., Goyal, A. (2018). Manno-oligosaccharides as Prebiotic-Valued Products from Agro-waste. In: Varjani, S., Parameswaran, B., Kumar, S., Khare, S. (eds) Biosynthetic Technology and Environmental Challenges. Energy, Environment, and Sustainability. Springer, Singapore. https://doi.org/10.1007/978-981-10-7434-9_12

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