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Clinical Investigation of Portal Hypertension pp 281–288Cite as

Endoscopic Treatment of Esophageal Varices: Bimonthly Endoscopic Variceal Ligation

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Abstract

Endoscopic variceal ligation (EVL) is being used increasingly to treat esophageal varices because of its safety and simplicity and because no sclerosant is required. However, early recurrence of esophageal varices after this procedure has been reported.

We compared the efficacy and long-term results of EVL performed in three treatments using a total of 16 O-rings at two different intervals, namely, biweekly (once every 2 weeks: the conventional interval) and bimonthly (once every 2 months). In all patients except two (both in the biweekly group), the esophageal varices were completely eradicated. Overall rates of both variceal recurrence and additional treatment were higher in the biweekly group than in the bimonthly group (P < 0.001).

EVL performed bimonthly in three treatment sessions for esophageal varices yielded better results than the same treatment performed biweekly. Treatment at the longer interval yielded a higher total eradication rate, lower recurrence rate, and lower rate of required additional treatment. Repeat treatment of EVL is useful; therefore, three treatment sessions should be considered as one course. Bimonthly EVL (three times in 4 months) might become a standard treatment for esophageal varices.

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Authors and Affiliations

  1. Department of Surgery, Nippon Medical School Hospital, Tokyo, Japan

    Hiroshi Yoshida, Yasuhiro Mamada & Eiji Uchida

  2. Department of Surgery, Nippon Medical School Tama Nagayama Hospital, Tokyo, Japan

    Hiroshi Makino, Tadashi Yokoyama, Hiroshi Maruyama, Atsushi Hirakata, Junji Ueda & Hideyuki Takata

  3. Department of Surgery, Nippon Medical School Musashi Kosugi Hospital, Tokyo, Japan

    Nobuhiko Taniai

Authors
  1. Hiroshi Yoshida
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  2. Hiroshi Makino
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  3. Tadashi Yokoyama
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  4. Hiroshi Maruyama
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  5. Atsushi Hirakata
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  6. Junji Ueda
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  7. Hideyuki Takata
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  8. Yasuhiro Mamada
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  9. Nobuhiko Taniai
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  10. Eiji Uchida
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Corresponding author

Correspondence to Hiroshi Yoshida .

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Editors and Affiliations

  1. Department of Advanced Gastrointestinal Endoscopy, Fukushima Medical University, Fukushima, Japan

    Katsutoshi Obara

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© 2019 Springer Nature Singapore Pte Ltd.

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Yoshida, H. et al. (2019). Endoscopic Treatment of Esophageal Varices: Bimonthly Endoscopic Variceal Ligation. In: Obara, K. (eds) Clinical Investigation of Portal Hypertension. Springer, Singapore. https://doi.org/10.1007/978-981-10-7425-7_27

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  • DOI: https://doi.org/10.1007/978-981-10-7425-7_27

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-7424-0

  • Online ISBN: 978-981-10-7425-7

  • eBook Packages: MedicineMedicine (R0)

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