Exploring the Multifaceted Role of Microbes in Pharmacology
With the continuous growth in human population, rising incidence and predominance of various diseases, there is growing need for development of natural as well as engineered diagnostic systems and drugs in order to meet the therapeutic demands. Since microorganisms have evolved in nature with an astounding set of mechanisms utilized in detecting and responding to varied, transient and enduring external stimuli, such microbial systems can be utilized in diagnosis as well as giving competition to animal cells in producing value added products due to its easy and low cost processing. The re-making of various biosensing systems by incorporating whole cells intend to provide efficient biological detection and measurable response. Microbes governing the synthesis of biopolymers are also found to be exploited in developing new generation of novel drug delivery systems and as repair material of tissues. The area of synthetic biology together with novel microbial systems and whole cells is gaining rapid attention in diagnostics and global health challenges. With this background, the present chapter highlights various applications of microbes in pharmaceutical industries with special emphasis on diagnosis and drug delivery.
KeywordsAntibiotics Drug delivery Enzyme inhibitor Microbes
The authors are thankful to Director, MNNIT Allahabad for providing necessary research facilities and acknowledge the support of MHRD sponsored project “Design and Innovation Centre” and Centre for Medical Diagnostic and Research (CMDR), MNNIT Allahabad.
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