Continuous Glucose Monitoring and Glycemic Variability

  • J. Zhou
  • W. JiaEmail author


Glycemic variability refers to the unstable state of glucose levels fluctuating from its peaks to valleys. With a deep understanding of glycemic variability, more and more evidence shows that glycemic variability contributes to the development of chronic complications of diabetes mellitus. Glycemic variability has become an important aspect of glycemic control. In recent years, the association between glycemic variability and diabetic complications has become a research hot spot. Currently, with the use of continuous glucose monitoring (CGM) technology for comprehensive assessment of glycemic variability in diabetic patients, the association between glycemic variability and diabetic complications has been reported in both type 1 and type 2 diabetic patients. This chapter will introduce the role of glycemic variability in diabetic microvascular and macrovascular complications and will discuss the relationship between glycemic variability and islet functions.


Glycemic variability Diabetic microvascular complications Diabetic macrovascular complications Continuous glucose monitoring 


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© Springer Nature Singapore Pte Ltd. and Shanghai Scientific and Technical Publishers 2018

Authors and Affiliations

  1. 1.Department of Endocrinology and Metabolism, Shanghai Clinical Center for Diabetes, Shanghai Diabetes InstituteShanghai Jiao Tong University, Affiliated Sixth People’s HospitalShanghaiChina

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