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Gum Arabic Based Multiple Units for Oral Drug Delivery

  • Amit Kumar NayakEmail author
  • Md Saquib Hasnain
Chapter
Part of the SpringerBriefs in Applied Sciences and Technology book series (BRIEFSAPPLSCIENCES)

Abstract

GAr is a plant-derived natural polysaccharidic gum, which is originally extracted from Acacia nilotica tree, belonging to the family, Leguminosae (Ali et al. in Food Chem Toxicol 47:1–8, 2009; Dauqan and Abdullah in Am J Appl Sci 10:1270–1279, 2013).

References

  1. B.H. Ali, A. Ziada, G. Blunden, Biological effects of gum arabic: a review of some recent research. Food Chem. Toxicol. 47, 1–8 (2009)CrossRefGoogle Scholar
  2. S.Y. Alkarib, D.E. Mohamed Elhassan, A.O. Nur, Evaluation of gum Arabic as a film coating former for immediate release oral tablet formulation. World J. Pharm. Pharmaceut. Sci. 5, 32–41 (2016)Google Scholar
  3. M.R. Avadi, A.M.M. Sadeghi, N. Mohammadpour, S. Abedin, F. Atyabi, R. Dinarvand, M. Rafiee-Tehrani (2010) Preparation and characterization of insulin nanoparticles using chitosan and Arabic gum with ionotropic gelation method. Nanomed: Nanotechnol. Biol. Med. 6, 58–63Google Scholar
  4. E. Dauqan, A. Abdullah, Utilization of gum Arabic for industries and human health. Am. J. Appl. Sci. 10, 1270–1279 (2013)CrossRefGoogle Scholar
  5. P.S. Gils, D. Ray, P.K. Sahoo, Designing of silver nanoparticles in gum arabic based semi-IPN hydrogel. Int. J. Biol. Macromol. 46, 237–244 (2010)CrossRefGoogle Scholar
  6. V. Heuzé, H. Thiollet, G. Tran, P. Hassoun, D. Bastianelli, F. Lebas (2016) Gum arabic tree (Acacia senegal). Feedipedia, a programme by INRA, CIRAD, AFZ and FAO. https://www.feedipedia.org/node/342
  7. A.K. Jha, D. Chetia, Development of natural gum based fast disintegrating tablets of glipizide. Asian J. Pharm. 6, 282–288 (2012)CrossRefGoogle Scholar
  8. P. Kadare, P. Maposa, A. Dube, C.C. Maponga (2014) Encapsulation of isoniazid in chitosan-gum arabic and poly (lactic-co-glycolic acid) PVA particles to provide a sustained release formulation. J. Pharmaceut. Pharmacol. S(1), 1–6Google Scholar
  9. E.X. Lu, Z.Q. Jiang, Q.Z. Zhang, X.G. Jiang, A water-insoluble drug monolithic osmotic tablet system utilizing gum arabic as an osmotic, suspending, and expanding agent. J. Control Rel. 92, 375–382 (2003)CrossRefGoogle Scholar
  10. A.M. Mariana, L.B. María, V. Lorena, D.B. Claudio, Gum Arabic: More than an edible emulsifier. Products Appl. Biopolym. (2012).  https://doi.org/10.5772/33783
  11. A.K. Mistry, C.D. Nagda, D.C. Nagda, B.C. Dixit, R.B. Dixit, Formulation and in vitro evaluation of ofloxacin tablets using natural gums as binders. Sci. Pharm. 82, 441–448 (2014)CrossRefGoogle Scholar
  12. A.K. Nayak, B. Das, R. Maji, Calcium alginate/gum Arabic beads containing glibenclamide: Development and in vitro characterization. Int. J. Biol. Macromol. 51, 1070–1078 (2012)CrossRefGoogle Scholar
  13. K.K. Nishi, A. Jayakrishnan, Self-gelling primaquine-gum arabic conjugate: an injectable controlled delivery system for primaquine. Biomacromol 8, 84–90 (2007)CrossRefGoogle Scholar
  14. S. Patel, A. Goyal, Applications of natural polymer gum Arabic: a review. Int. J. Food Prop. 18, 986–998 (2015)CrossRefGoogle Scholar
  15. J.L.A. Webb, The trade in gum Arabic: prelude to French conquest in Senegal. J. Afr. Hist. 26, 149–168 (2009)CrossRefGoogle Scholar
  16. M.P. Yadav, J.M. Igartuburu, Y. Yan, E.A. Nothnagel, Chemical investigation of the structural basis of the emulsifying activity of gum arabic. Food Hydrocol 21, 297–308 (2007)CrossRefGoogle Scholar
  17. D. Yael, C. Yachin, Y. Rachel, Structure of gum Arabic in aqueous solution. J. Polym.Sci 44, 3265–3271 (2006)CrossRefGoogle Scholar

Copyright information

© The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Department of PharmaceuticsSeemanta Institute of Pharmaceutical SciencesMayurbhanjIndia
  2. 2.Department of PharmacyShri Venkateshwara UniversityAmrohaIndia

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