Transcription Factors in Gastrointestinal Malignancies
Gastrointestinal cancer are complex diseases and most lethal amongst all other cancer types. Recent studies have revealed that transcriptional factors are ubiquitously expressed and modulates various physiological processes such as progression and metastasis in Gastrointestinal malignancies. Therefore, targeting these transcriptional factors is an important therapeutic strategy against cancer. In this book, we will discuss some of the important transcriptional factors in depth and further evaluate their role in Gastrointestinal malignancies.
KeywordsGastrointestinal malignancies Transcription factors NF-κB HIF-1α AP1 E2-F1 STAT-3
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