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Proteases—The Sharp Scissors in Human Diseases

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Pathophysiological Aspects of Proteases

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Abstract

Cells use proteases to accomplish a variety of cellular functions primarily through activation or deactivation of target proteins. An interruption in the balance between activation and deactivation is implicated in a growing list of human diseases. This chapter briefly covers the classification of the human proteases along with their involvement in diseases finally concluding with the idea of protease inhibitors as drugs and mention of related databases.

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Author information

Authors and Affiliations

  1. Department of Physical Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata, 700032, West Bengal, India

    Sandipan Chakraborty

  2. Department of Microbiology, University of Calcutta, 35 Ballygunge Circular Road, Kolkata, 700019, West Bengal, India

    Soumalee Basu

Authors
  1. Sandipan Chakraborty
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  2. Soumalee Basu
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Correspondence to Soumalee Basu .

Editor information

Editors and Affiliations

  1. Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India

    Sajal Chakraborti

  2. Institute of Cardiovascular Sciences, University of Manitoba, Manitoba, Canada

    Naranjan S. Dhalla

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Chakraborty, S., Basu, S. (2017). Proteases—The Sharp Scissors in Human Diseases. In: Chakraborti, S., Dhalla, N. (eds) Pathophysiological Aspects of Proteases. Springer, Singapore. https://doi.org/10.1007/978-981-10-6141-7_27

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