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Cyanidioschyzon merolae pp 177–185Cite as

Cell Cycle and Organelle Division Cycle in Cyanidioschyzon merolae

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Abstract

A cell replicates by duplicating cellular contents and then dividing into two daughter cells. This is known as the cell cycle, which is characterized by the dynamics of the cell nucleus. However, eukaryotic cells contain organelles other than the nucleus, such as mitochondria, chloroplasts, peroxisomes, endoplasmic reticulum (ER), Golgi bodies, and vacuoles. To understand reproduction of cells, the division and inheritance of organelles as well as the mitotic cycle should be investigated. However, model animal cells and plant cells contain multiples of these organelles which exhibit complex shapes. Therefore, it has been difficult to elucidate their division and inheritance. In contrast, the red alga Cyanidioschyzon merolae possesses a minimum set of organelles. Because of its simple cellular architecture, the dynamics and mechanisms underlying its cell division and inheritance have been investigated. In addition, cell cycle stages of C. merolae have been determined using an S phase-specific marker proliferating cell nuclear antigen (PCNA) and an M phase-specific marker H3S10ph. In this chapter, I introduce the timing of division and inheritance of organelles during the cell cycle in C. merolae and application of the synchronous culture to transcriptome analysis for identifying novel genes related to the division and inheritance of organelles.

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Acknowledgments

Our study was partly supported was by JSPS KAKENHI (no. JP15K18588 to T.F.; no. 25251039 to S.M.) and by the Core Research for Evolutional Science and Technology Program of the Japan Science and Technology Agency (S.M.).

Author information

Authors and Affiliations

  1. Department of Cell Genetics, National Institute of Genetics, 1111 Yata, Mishima, Shi-zuoka, 411-8540, Japan

    Takayuki Fujiwara

  2. Department of Genetics, Graduate University for Advanced Studies (SOKENDAI), 1111 Yata, Mishima, Shizuoka, 411-8540, Japan

    Takayuki Fujiwara

  3. Japan Science and Technology Agency, CREST, 4-1-8 Honcho, Kawaguchi, Saitama, 332-0012, Japan

    Takayuki Fujiwara

Authors
  1. Takayuki Fujiwara
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Corresponding author

Correspondence to Takayuki Fujiwara .

Editor information

Editors and Affiliations

  1. Faculty of Science Department of Chemical and Biological Sciences, Japan Women’s University, Tokyo, Japan

    Tsuneyoshi Kuroiwa

  2. Department of Cell Genetics, National Institute of Genetics, Shizuoka, Japan

    Shinya Miyagishima

  3. Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Chiba, Japan

    Sachihiro Matsunaga

  4. Department of Life Sciences Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan

    Naoki Sato

  5. Department of Biological Sciences Graduate School of Science, University of Tokyo, Tokyo, Japan

    Hisayoshi Nozaki

  6. Laboratory for Chemistry and Life Science Institute of Innovative Research, Tokyo Institute of Technology, Kanagawa, Japan

    Kan Tanaka

  7. Graduate School of Science and Technology for Innovation Faculty of Science, Department of Biological Science and Chemistry, Yamaguchi University, Yamaguchi, Japan

    Osami Misumi

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Fujiwara, T. (2017). Cell Cycle and Organelle Division Cycle in Cyanidioschyzon merolae . In: Kuroiwa, T., et al. Cyanidioschyzon merolae. Springer, Singapore. https://doi.org/10.1007/978-981-10-6101-1_11

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