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Design and Application of Injectable Gels in Tissue Engineering and Drug Delivery

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Polymer Gels

Part of the book series: Gels Horizons: From Science to Smart Materials ((GHFSSM))

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Abstract

Injectable gels offer several advantages such as minimally invasive, targeted delivery, regenerate damaged tissues and organs, support cell proliferation and differentiation, and facilitate tissue growth. They are prepared from carbon-based biomaterials such as carbon nanotubes and graphene oxide, natural and synthetic polymers. In the design of injectable gels, the properties of the material used influence their application. Injectable gels have been investigated for delivery of bioactive agents such as anticancer, antimalarials, antihyperglycemic, antiviral, anti-inflammatory, antimicrobial. They are also used for wound dressing and regenerative medicine such as bone regeneration. This chapter will focus on the design and therapeutic efficacy of the currently developed injectable gels.

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Acknowledgements

The financial assistance of Medical Research Council (Self-Initiated Research) and National Research Foundation, South Africa towards this research are hereby acknowledged. The views and opinions expressed in this manuscript are those of the author and not of MRC or NRF.

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  1. Department of Chemistry, University of Fort Hare, Alice Campus, Alice, South Africa

    B. A. Aderibigbe

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  1. Faculty in Manufacturing, Enhanced Composites and Structures Centre, School of Aerospace, Transport and Manufacturing, Cranfield University, Cranfield, United Kingdom

    Vijay Kumar Thakur

  2. Division of Chemistry, Government Degree College Bhoranj, Himachal Pradesh University, Shimla, Himachal Pradesh, India

    Manju Kumari Thakur

  3. Department of Analytical Chemistry and Environmental Engineering, and Advance Polymer Materials Group, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, Bucharest, Romania

    Stefan Ioan Voicu

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Aderibigbe, B.A. (2018). Design and Application of Injectable Gels in Tissue Engineering and Drug Delivery. In: Thakur, V., Thakur, M., Voicu, S. (eds) Polymer Gels. Gels Horizons: From Science to Smart Materials. Springer, Singapore. https://doi.org/10.1007/978-981-10-6080-9_12

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