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Reconstitution of Motor Protein ATPase

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Supramolecular Chemistry of Biomimetic Systems

Abstract

Molecular motor proteins are amazing biological units that are responsible for the transformation of the chemical or biological components into mechanical works. These molecular machines express stronger energy conversion than man-made systems, which inspired scientists to pursue the target of improved performance of current synthetic devices. Thus, it is significant to explore interesting features of biomolecular motors, and design the novel intelligent platforms that mixed motor proteins with synthetic materials. Biomimetic molecular assembly enables the possibility for the in vitro reconstruction of biomolecular motors, further provides a variety of functionalized strategies. In this chapter, we gave a detailed introduction for one of the most familiar biomolecular motors, adenosine triphosphatase (ATPase), and deepen the understanding of their working mechanism and clarified how to conjugate ATPase with the artificially synthetic materials. In addition, some promising examples and significant comments were highlighted to display reconstructed performance of ATPase during this exploring voyage.

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Authors and Affiliations

  1. Beijing National Laboratory for Molecular Sciences (BNLMS), CAS Key Lab of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China

    Mingjun Xuan, Yi Jia & Junbai Li

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  1. Mingjun Xuan
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  2. Yi Jia
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  1. Institute of Chemistry, Chinese Academy of Sciences, Beijing, China

    Junbai Li

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Xuan, M., Jia, Y., Li, J. (2017). Reconstitution of Motor Protein ATPase. In: Li, J. (eds) Supramolecular Chemistry of Biomimetic Systems. Springer, Singapore. https://doi.org/10.1007/978-981-10-6059-5_10

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