Animal Models of Tardive Dyskinesia

Abstract

Today we are in an era of utmost modernization; technology used in medical science says hats off to human mind. We have left no pebbles unturned in discovering human “BRAIN.” Researchers have gone deep into lobes then whether its physiology of brain or vast anatomical features. Irrespective of all the laurels attained in it, there is no suitable treatment for some of the CNS disorders, for which patients are paying its cost with their lives. One such example is of schizophrenia from which tardive dyskinesia (TD) occurs as a side effect. Throwing some light on the preclinical work done on TD, a review is presented to put together the toxic agents causing TD. Hoping it could prove fruitful in a process of attenuation or abolition of TD. Schizophrenia was conceived by Eugen Bleuler in 1950. It has its onset during puberty and lasts throughout life. Neuroleptics are universally prescribed psychotropic drugs for schizophrenia from which TD emerged as side effect.