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Animal Models of Autism

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Animal Models of Neurological Disorders

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Abstract

Autism is a neurodevelopment disorder that arises in approximately 1% of the worldwide population. Autism is a lifelong condition characterized by repetitive behavior and impaired socialization, abnormalities in communication, restricted and repetitive behavior that usually occurs in the first 3 years of life. Besides from these important symptoms, a significant number of autism individuals display higher levels of anxiety and exhibit impaired emotional learning. The most remarkable features of the social impairments in autism are defects in coordinating visual attention with others. External ear malformations are the most common physical abnormality associated with autism. About 30% individuals of autism spectrum disorder (ASD) engage in self-harming behaviors such as head banging and hand biting (Dominick et al. 2007; Johnson et al. 2007). Sir Leo Kanner in 1943 firstly described autism by as “children which are locked within them.” Around 400,000 children are affected by autism in America, with 1–2 new cases per 1,000 births in the USA.

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Authors and Affiliations

  1. Department of Pharmacology, ISF College of Pharmacy, Moga, 142001, Punjab, India

    Nidhika Sharma, Sumit Jamwal & Puneet Kumar Bansal

  2. Department of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University (State Govt. University), Bathinda, Punjab, India

    Puneet Kumar Bansal

Authors
  1. Nidhika Sharma
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  2. Sumit Jamwal
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  3. Puneet Kumar Bansal
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Correspondence to Puneet Kumar Bansal .

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Editors and Affiliations

  1. Department of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University (State Govt. University), Bathinda, Punjab, India

    Puneet Kumar Bansal

  2. Department of Pharmacology, ISF College of Pharmacy, Moga, Punjab, India

    Rahul Deshmukh

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Sharma, N., Jamwal, S., Bansal, P.K. (2017). Animal Models of Autism. In: Bansal, P., Deshmukh, R. (eds) Animal Models of Neurological Disorders. Springer, Singapore. https://doi.org/10.1007/978-981-10-5981-0_15

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