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Epidemiology of Atopic Dermatitis in Japan

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Evolution of Atopic Dermatitis in the 21st Century

Abstract

Atopic dermatitis (AD) is a common, chronic, and eczematous skin disease. The prevalence of AD is increasing worldwide and varies among countries. AD prevalence in regions with different climates even within a country is different. A number of genetic mutations have been implicated in the development of AD. Mutations in the filaggrin gene and its frequencies are different between different populations. A wide range in AD prevalence and a rapid increase in prevalence strongly indicate that environmental factors play crucial roles in development of AD. Epigenetics might be key to understanding genetic-environmental interactions in this disease.

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Author information

Authors and Affiliations

  1. Department of Pediatrics, Gunma University Graduate School of Medicine, 3-35-22 Showa, Gunma, 371 8511, Japan

    Takumi Takizawa M.D., Ph.D., Akihiro Morikawa M.D., Ph.D. & Hirokazu Arakawa M.D., Ph.D.

Authors
  1. Takumi Takizawa M.D., Ph.D.
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  2. Akihiro Morikawa M.D., Ph.D.
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  3. Hirokazu Arakawa M.D., Ph.D.
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Corresponding author

Correspondence to Takumi Takizawa M.D., Ph.D. .

Editor information

Editors and Affiliations

  1. Department of Dermatology, Integrated Medicine, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan

    Ichiro Katayama

  2. Department of Dermatology, Integrated Medicine, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan

    Hiroyuki Murota

  3. Department of Dermatology, National Defense Medical College, Tokorosazawa, Saitama, Japan

    Takahiro Satoh

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Takizawa, T., Morikawa, A., Arakawa, H. (2018). Epidemiology of Atopic Dermatitis in Japan. In: Katayama, I., Murota, H., Satoh, T. (eds) Evolution of Atopic Dermatitis in the 21st Century. Springer, Singapore. https://doi.org/10.1007/978-981-10-5541-6_2

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  • DOI: https://doi.org/10.1007/978-981-10-5541-6_2

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  • Online ISBN: 978-981-10-5541-6

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