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Quorum Sensing: Melody Beneath the Ground

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Plant Microbiome: Stress Response

Part of the book series: Microorganisms for Sustainability ((MICRO,volume 5))

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Abstract

Quorum sensing (QS) systems allow bacterial organisms to coordinate their behavior depending on the local population density and are used in many artificial systems requiring cell-to-cell communication. The accumulation of optimum stimulatory levels of autoinducers is detected by bacteria that affect the gene expression of their behavior. QS bacteria defer the production of virulence factors until cell numbers reach optimum levels, resulting in infection leading to activation of the host immune system by secretion of virulence factors causing productive infection. It is a successful technique that coordinates the gene expression of groups of organisms. In this chapter, the mechanisms pertaining to varied bacterial QS systems are presented and discussed. The differences between two definitive bacterial signal transduction systems are also discussed. We contend that the bacterial QS systems are optimally intended to specifically translate extracellular autoinducer information into internal changes via gene expression. In addition, the different bacterial QS systems used in deciphering basic mechanisms underlying the advancement of bacterial communities are discussed. Here, we review the updated advancements of the genetic approaches in engineering QS circuits to utilize bacterial communication in environmental biotechnology.

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References

  • Ansaldi M, Marolt D, Stebe T, Mandic-Mulec I, Dubnau D (2002) Specific activation of the Bacillus quorum- sensing systems by isoprenylated pheromone variants. Mol Microbiol 44:1561–1573

    Article  CAS  PubMed  Google Scholar 

  • Balaban N, Novick RP (1995) Translation of RNAIII, the Staphylococcus aureus agr regulatory RNA molecule, can be activated by a 39-end deletion. FEMS Microbiol Lett 133:155–161

    CAS  PubMed  Google Scholar 

  • Bendiak GN, Ratjen F (2009) The approach to Pseudomonas aeruginosa in cystic fibrosis. Semin Respir Crit Care Med 30:587–595

    Article  PubMed  Google Scholar 

  • Benito Y, Kolb FA, Romby P, Lina G, Etienne J, Vandenesch F (2000) Probing the structure of RNAIII, the Staphylococcus aureus agr regulatory RNA, and identification of the RNA domain involved in repression of protein A expression. RNA 6:668–679

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Bodey GP, Bolivar R, Fainstein V, Jadeja L (1983) Infections caused by Pseudomonas aeruginosa. Rev Infect Dis 5:279–313

    Article  CAS  PubMed  Google Scholar 

  • Booth MC, Bogie CP, Sahl HG, Siezen RJ, Hatter KL, Gilmore MS (1996) Structural analysis and proteolytic activation of Enterococcus faecalis cytolysin, a novel lantibiotic. Mol Microbiol 21:1175–1184

    Article  CAS  PubMed  Google Scholar 

  • Booth MC, Cheung AL, Hatter KL, Jett BD, Callegan MC, Gilmore MS (1997) Staphylococcal accessory regulator (sar) in conjunction with agr contributes to Staphylococcus aureus virulence in endophthalmitis. Infect Immun 65:1550–1556

    CAS  PubMed  PubMed Central  Google Scholar 

  • Bowden MG, Chen W, Singvall J, Xu Y, Peacock SJ, Valtulina V, Speziale P, Hook M (2005) Identification and preliminary characterization of cell-wall-anchored proteins of Staphylococcus epidermidis. Microbiology 151:1453–1464

    Article  CAS  PubMed  Google Scholar 

  • Chater KF, Horinouchi S (2003) Signaling early developmental events in two highly diverged Streptomyces species. Mol Microbiol 48:9–15

    Article  CAS  PubMed  Google Scholar 

  • Cheung AL, Eberhardt KJ, Chung E, Yeaman MR, Sullam PM, Ramos M, Bayer AS (1994) Diminished virulence of a sar2/agr2 mutant of Staphylococcus aureus in the rabbit model of endocarditis. J Clin Invest 94:1815–1822

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Chugani SA, Whiteley M, Lee KM, D’Argenio D, Manoil C, Greenberg EP (2001) QscR, a modulator of quorum-sensing signal synthesis and virulence in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A 98:2752–2757

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Cirioni O, Ghiselli R, Minardi D, Orlando F, Mocchegiani F, Silvestri C, Muzzonigro G, Saba V, Scalise G (2007) RNAIII-inhibiting peptide affects biofilm formation in a rat model of staphylococcal ureteral stent infection. Antimicrob Agents Chemother 51:4518–4520

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Davies DG, Parsek MR, Pearson JP, Iglewski BH, Costerton JW, Greenberg EP (1998) The involvement of cell-to-cell signals in the development of a bacterial biofilm. Science 280:295–298

    Article  CAS  PubMed  Google Scholar 

  • De Kievit TR, Iglewski BH (2000) Bacterial quorum sensing in pathogenic relationships. Infect Immun 68:4839–4849

    Article  PubMed  PubMed Central  Google Scholar 

  • DiMango E, Zar HJ, Bryan R, Prince A (1995) Diverse Pseudomonas aeruginosa gene products stimulate respiratory epithelial cells to produce interleukin-8. J Clin Invest 96:2204–2210

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Driscoll JA, Brody SL, Kollef MH (2007) The epidemiology, pathogenesis and treatment of Pseudomonas aeruginosa infections. Drugs 67:351–368

    Article  CAS  PubMed  Google Scholar 

  • Dufour P, Jarraud S, Vandenesch F, Greenland T, Novick RP et al (2002) High genetic variability of the agr locus in staphylococcus species. J Bacteriol 184:1180–1186

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Eberhard A, Burlingame AL, Eberhard C, Kenyon GL, Nealson KH, Oppenheimer NJ (1981) Structural identification of autoinducer of Photobacterium fischeri luciferase. Biochemistry 20:2444–2449

    Article  CAS  PubMed  Google Scholar 

  • Engebrecht J, Silverman M (1984) Identification of genes and gene products necessary for bacterial bioluminescence. Proc Natl Acad Sci U S A 81:4154–4158

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Engebrecht J, Nealson K, Silverman M (1983) Bacterial bioluminescence: isolation and genetic analysis of functions from Vibrio fischeri. Cell 32:773–781

    Article  CAS  PubMed  Google Scholar 

  • Erickson DL, Endersby R, Kirkham A, Stuber K, Vollman DD, Rabin HR, Mitchell I, Storey DG (2002) Pseudomonas aeruginosa quorum-sensing systems may control virulence factor expression in the lungs of patients with cystic fibrosis. Infect Immun 70:1783–1790

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Fleming V, Feil E, Sewell AK, Day N, Buckling A, Massey RC (2006) Agric interference between clinical Staphylococcus aureus strains in an insect model of virulence. J Bacteriol 188:7686–7688

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Fuqua C (2006) The QscR quorum-sensing regulon of Pseudomonas aeruginosa: an orphan claims its identity. J Bacteriol 188:3169–3171

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Fuqua C, Eberhard A (1999) Signal generation in autoinduction systems: synthesis of acylated homoserine lactones by LuxI-type proteins. In: Dunny GM, Winans SC (eds) Cell-cell signaling in bacteria. ASM Press, Washington, DC, pp 211–230

    Google Scholar 

  • George EA, Muir TW (2007) Molecular mechanisms of agr quorum sensing in virulent staphylococci. ChemBio 8:847–855

    Article  CAS  Google Scholar 

  • Gillaspy AF, Hickmon SG, Skinner RA, Thomas JR, Nelson CL, Smeltzer MS (1995) Role of the accessory gene regulator (agr) in pathogenesis of staphylococcal osteomyelitis. Infect Immun 63:3373–3380

    CAS  PubMed  PubMed Central  Google Scholar 

  • Goerke C, Kraning K, Stern M, Doring G, Botzenhart K, Wolz C (2000) Molecular epidemiology of community-acquired Staphylococcus Aureus in families with and without cystic fibrosis patients. J Infect Dis 181:984–989

    Article  CAS  PubMed  Google Scholar 

  • Gould TA, Schweizer HP, Churchill ME (2004) Structure of the Pseudomonas aeruginosa acylhomoserinelactone synthase LasI. Mol Microbiol 53:1135–1146

    Article  CAS  PubMed  Google Scholar 

  • Grumbein S, Opitz M, Lieleg O (2014) Selected metal ions protect Bacillus subtilis biofilms from erosion. Metallomics 6:1441–1450

    Article  CAS  PubMed  Google Scholar 

  • Heurlier K, Denervaud V, Haas D (2006) Impact of quorum sensing on fitness of Pseudomonas aeruginosa. Int J Med Microbiol 296:93–102

    Article  CAS  PubMed  Google Scholar 

  • Heyer G, Saba S, Adamo R, Rush W, Soong G, Cheung A, Prince A (2002) Staphylococcus aureus agr and sarA functions are required for invasive infection but not inflammatory responses in the lung. Infect Immun 70:127–133

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ivanova K, Fernandes MM, Tzanov T (2013) Current advances on bacterial pathogenesis inhibition and treatment strategies. In: Méndez-Vilas A (eds) Microbial pathogens and strategies for combating them: science, technology and education. Formatex Research Center, pp 322–336. https://doi.org/10.13140/RG.2.1.3988.7840

  • Ji G, Beavis RC, Novick RP (1995) Cell density control of staphylococcal virulence mediated by an octapeptide pheromone. Proc Natl Acad Sci U S A 92:12055–12059

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ji G, Beavis R, Novick RP (1997) Bacterial interference caused by auto inducing peptide variants. Science 276:2027–2030

    Article  CAS  PubMed  Google Scholar 

  • Kaplan HB, Greenberg EP (1985) Diffusion of autoinducer is involved in regulation of the Vibrio fischeri luminescence system. J Bacteriol 163:1210–1214

    CAS  PubMed  PubMed Central  Google Scholar 

  • Karatuna O, Yagci A (2010) Analysis of the quorum sensing dependent virulence factor production and its relationship with antimicrobial susceptibility in Pseudomonas aeruginosa respiratory isolates. Clin Microbiol Infect. https://doi.org/10.1111/j.1469-0691.2010.03177.x

  • Kehinde EO, Rotimi VO, Al-Hunayan A, Abdul-Halim H, Boland F, Al-Awadi KA (2004) Bacteriology of urinary tract infection associated with indwelling J ureteral stents. J Endourol 18:891–896

    Article  PubMed  Google Scholar 

  • Kielian T, Cheung A, Hickey WF (2001) Diminished virulence of an a-toxin mutant of Staphylococcus aureus in experimental brain abscesses. Infect Immun 69:6902–6911

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Koenig RL, Ray JL, Maleki SJ, Smeltzer MS, Hurlburt BK (2004) Staphylococcus aureus AgrA binding to the RNAIII-agr regulatory region. J Bacteriol 186:7549–7555

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kohler T, Buckling A, Van DC (2009) Cooperation and virulence of clinical Pseudomonas aeruginosa populations. Proc Natl Acad Sci U S A 106:6339–6344

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kong KF, Vuong C, Otto M (2006) Staphylococcus quorum sensing in biofilm formation and infection. Int J Med Microbiol 296:133–139

    Article  CAS  PubMed  Google Scholar 

  • Kravchenko VV, Kaufmann GF, Mathison JC, Scott DA, Katz AZ, Grauer DC, Lehmann M, Meijler MM, Janda KD, Ulevitch RJ (2008) Modulation of gene expression via disruption of NF-kB signaling by a bacterial small molecule. Science 321:259–263

    Article  CAS  PubMed  Google Scholar 

  • Latifi A, Foglino M, Tanaka K, Williams P, Lazdunski A (1996) A hierarchical quorum-sensing cascade in pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary-phase sigma factor RpoS. Mol Microbiol 21:1137–1146

    Article  CAS  PubMed  Google Scholar 

  • Lauderdale KJ, Boles BR, Cheung AL, Horswill AR (2009) Interconnections between sigma B, agr, and proteolytic activity in Staphylococcus aureus biofilm maturation. Infect Immun 77:1623–1635

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lina G, Jarraud S, Ji G, Greenland T, Pedraza A, Etienne J, Novick RP, Vandenesch F (1998) Transmembrane topology and histidine protein kinase activity of AgrC, the agr signal receptor in Staphylococcus aureus. Mol Microbiol 28:655–662

    Article  CAS  PubMed  Google Scholar 

  • Lyczak JB, Cannon CL, Pier GB (2000) Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist. Microbes Infect 2:1051–1060

    Article  CAS  PubMed  Google Scholar 

  • Lyon GJ, Novick RP (2004) Peptide signaling in Staphylococcus aureus and other Gram-positive bacteria. Peptides 25:1389–1403

    Article  CAS  PubMed  Google Scholar 

  • Lyon GJ, Wright JS, Muir TW, Novick RP (2002) Key determinants of receptor activation in the agr autoinducing peptides of Staphylococcus aureus. Biochemistry 41:10095–10104

    Article  CAS  PubMed  Google Scholar 

  • Manefield M, Turner SL (2002) Quorum sensing in context: out of molecular biology and into microbial ecology. Microbiology 148:3762–3764

    Article  CAS  PubMed  Google Scholar 

  • Marketon MM, Gronquist MR, Eberhard A, Gonzalez JE (2002) Characterization of the Sinorhizobium meliloti sinR/sinI locus and the production of novel N-acyl homoserine lactones. J Bacteriol 184:5686–5695

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Massey RC, Horsburgh MJ, Lina G, Hook M, Recker M (2006) The evolution and maintenance of virulence in Staphylococcus aureus: a role for host-to-host transmission. Nat Rev Microbiol 4:953–958

    Article  CAS  PubMed  Google Scholar 

  • Mayville P, Ji G, Beavis R, Yang H, Goger M, Novick RP, Muir TW (1999) Structure-activity analysis of synthetic autoinducing thiolactone peptides from Staphylococcus aureus responsible for virulence. Proc Natl Acad Sci U S A 96:1218–1223

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mishler DM, Topp S, Reynoso CMK, Gallivan JP (2010) Engineering bacteria to recognize and follow small molecules. Curr Opin Biotechnol 21(5):653–656. https://doi.org/10.1016/j.copbio.2010.05.007

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • More MI, Finger LD, Stryker JL, Fuqua C, Eberhard A, Winans SC (1996) Enzymatic synthesis of a quorum-sensing autoinducer through use of defined substrates. Science 272:1655–1658

    Article  CAS  PubMed  Google Scholar 

  • Morfeldt E, Taylor D, Von GA, Arvidson S (1995) Activation of a-toxin translation in Staphylococcus aureus by the trans encoded antisense RNA, RNAIII. EMBO J 14:4569–4577

    CAS  PubMed  PubMed Central  Google Scholar 

  • Mulcahy H, Charron-Mazenod L, Lewenza S (2010) Pseudomonas aeruginosa produces an extracellular deoxyribonuclease that is required for utilization of DNA as a nutrient source. Environ Microbiol 12:1621–1629

    CAS  PubMed  Google Scholar 

  • Nakayama J, Cao Y, Horii T, Sakuda S, Akkermans AD, de Vos WM, Naqasawa H (2001) Gelatinase biosynthesisactivating pheromone: a peptide lactone that mediates a quorum sensing in enterococcus faecalis. Mol Microbiol 41:145–154

    Article  CAS  PubMed  Google Scholar 

  • Nealson KH, Hastings JW (1979) Bacterial bioluminescence: its control and ecological significance. Microbiol Rev 43:496–518

    CAS  PubMed  PubMed Central  Google Scholar 

  • Novick RP (2003) Autoinduction and signal transduction in the regulation of staphylococcal virulence. Mol Microbiol 48:1429–1449

    Article  CAS  PubMed  Google Scholar 

  • Novick RP, Geisinger E (2008) Quorum sensing in staphylococci. Annu Rev Genet 42:541–564

    Article  CAS  PubMed  Google Scholar 

  • Novick RP, Ross HF, Projan SJ, Kornblum J, Kreiswirth B, Moghazeh S (1993) Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA molecule. EMBO J 12:3967–3975

    CAS  PubMed  PubMed Central  Google Scholar 

  • Novick RP, Projan SJ, Kornblum J, Ross HF, Ji G, Kreiswirth B, Vandenesch F, Moghazeh S (1995) The agr P2 operon: an autocatalytic sensory transduction system in Staphylococcus aureus. Mol Gen Genet 248:446–458

    Article  CAS  PubMed  Google Scholar 

  • Otto M, Sussmuth R, Jung G, Gotz F (1998) Structure of the pheromone peptide of the Staphylococcus epidermidis agr system. FEBS Lett 424:89–94

    Article  CAS  PubMed  Google Scholar 

  • Parsek MR, Tolker-Nielsen T (2008) Pattern formation in Pseudomonas aeruginosa biofilms. Curr Opin Microbiol 11:560–566

    Article  CAS  PubMed  Google Scholar 

  • Parsek MR, Val DL, Hanzelka BL, Cronan JE, Greenberg EP (1999) Acyl homoserinelactone quorum-sensing signal generation. Proc Natl Acad Sci U S A 96:4360–4365

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Pearson JP, Van Delden C, Iglewski BH (1999) Active efflux and diffusion are involved in transport of Pseudomonas aeruginosa cell-to-cell signals. J Bacteriol 181:1203–1210

    CAS  PubMed  PubMed Central  Google Scholar 

  • Roux A, Payne SM, Gilmore MS (2009) Microbial telesensing: probing the environment for friends, foes, and food. Cell Host Microbe 6:115–124

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Saenz HL, Augsburger V, Vuong C, Jack RW, Gotz F, Otto M (2000) Inducible expression and cellular location of AgrB, a protein involved in the maturation of the staphylococcal quorum-sensing pheromone. Arch Microbiol 174:452–455

    Article  CAS  PubMed  Google Scholar 

  • Sandoz KM, Mitzimberg SM, Schuster M (2007) Social cheating in Pseudomonas aeruginosa quorum sensing. Proc Natl Acad Sci U S A 104:15876–15881

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Schu DJ, Scruggs JM, Geissinger JS, Michel KG, Stevens AM (2014) Acyl-homoserine lactone recognition and response hindering the quorum-sensing regulator EsaR. PLoS One 9:e107687

    Article  PubMed  PubMed Central  Google Scholar 

  • Schuster M, Greenberg EP (2006) A network of networks: quorum-sensing gene regulation in Pseudomonas aeruginosa. Int J Med Microbiol 296:73–81

    Article  CAS  PubMed  Google Scholar 

  • Schuster M, Lostroh CP, Ogi T, Greenberg EP (2003) Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis. J Bacteriol 185:2066–2079

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Smith RS, Iglewski BH (2003) P. aeruginosa quorum-sensing systems and virulence. Curr Opin Microbiol 6:56–60

    Article  CAS  PubMed  Google Scholar 

  • Smith RS, Harris SG, Phipps R, Iglewski B (2002) The Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl) homoserine lactone contributes to virulence and induces inflammation in vivo. J Bacteriol 184:1132–1139

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Steinmoen H, Teigen A, Havarstein LS (2003) Competence-induced cells of Streptococcus pneumoniae lyse competence-deficient cells of the same strain during cocultivation. J Bacteriol 185:7176–7183

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Stevens AM, Dolan KM, Greenberg EP (1994) Synergistic binding of the Vibrio fischeri LuxR transcriptional activator domain and RNA polymerase to the lux promoter region. Proc Natl Acad Sci U S A 91:12619–12623

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Tenover FC, Gaynes RP (2000) The epidemiology of Staphylococcus aureus infections. In: Fischetti VA, Novick RP, Ferretti JJ, Portnoy DA, Rood JI (eds) Gram- positive pathogens. ASM Press, Washington, DC, pp 414–421

    Google Scholar 

  • Vannini A, Volpari C, Gargioli C, Muraglia E, Cortese R, De Francesco R, Neddermann P, Marco SD (2002) The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA. EMBO J 21:4393–4401

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Visick KL, Foster J, Doino J, McFall-Ngai M, Ruby EG (2000) Vibrio fischeri lux genes play an important role in colonization and development of the host light organ. J Bacteriol 182:4578–4586

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Vuong C, Saenz HL, Gotz F, Otto M (2000) Impact of the agr quorum-sensing system on adherence to polystyrene in Staphylococcus aureus. J Infect Dis 182:1688–1693

    Article  CAS  PubMed  Google Scholar 

  • Watson WT, Minogue TD, Val DL, Von Bodman SB, Churchill ME (2002) Structural basis and specificity of acyl-homoserine lactone signal production in bacterial quorum sensing. Mol Cell 9:685–694

    Article  CAS  PubMed  Google Scholar 

  • Whitehead NA, Barnard AM, Slater H, Simpson NJ, Salmond GP (2001) Quorum-sensing in Gram-negative bacteria. FEMS Microbiol Rev 25:365–404

    Article  CAS  PubMed  Google Scholar 

  • Wright JS, Traber KE, Corrigan R, Benson SA, Musser JM, Novick RP (2005) The agr radiation: an early event in the evolution of staphylococci. J Bacteriol 187:5585–5594

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Yao Y, Vuong C, Kocianova S, Villaruz AE, Lai Y, Sturdevant DE, Otto M (2006) Characterization of the Staphylococcus epidermidis accessory-gene regulator response: quorum-sensing regulation of resistance to human innate host defense. J Infect Dis 193:841–848

    Article  PubMed  Google Scholar 

  • Yarwood JM, Bartels DJ, Volper EM, Greenberg EP (2004) Quorum sensing in Staphylococcus aureus biofilms. J Bacteriol 186:1838–1850

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Yoon SS, Hennigan RF, Hilliard GM, Ochsner UA, Parvatiyar K, Kamani MC, Allen HL, DeKievit TR, Gardner PR, Schwab U, Rowe JJ, Iglewski BH, McDermott TR, Mason RP, Wozniak DJ, Hancock RE, Parsek MR, Noah TL, Boucher RC, Hassett DJ (2002) Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis. Dev Cell 3:593–603

    Article  CAS  PubMed  Google Scholar 

  • Zhang RG, Pappas T, Brace JL, Miller PC, Oulmassov T, Molyneaux JM, Anderson JC, Bashkin JK, Winans SC, Joachimiak A (2002) Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA. Nature 417:971–974

    Article  CAS  PubMed  Google Scholar 

  • Zhang L, Lin J, Ji G (2004) Membrane anchoring of the AgrD Nterminal amphipathic region is required for its processing to produce a quorum-sensing pheromone in Staphylococcus aureus. J Biol Chem 279:19448–19456

    Article  CAS  PubMed  Google Scholar 

  • Zhu J, Winans SC (1999) Autoinducer binding by the quorum-sensing regulator TraR increases affinity for target promoters in vitro and decreases TraR turnover rates in whole cells. Proc Natl Acad Sci U S A 96:4832–4837

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Zhu J, Winans SC (2001) The quorum-sensing transcriptional regulator TraR requires its cognate signaling ligand for protein folding, protease resistance, and dimerization. Proc Natl Acad Sci U S A 98:1507–1512

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Department of Environmental Science, Govt SAM Degree College, Budgam, 191111, Jammu & Kashmir, India

    Javid A. Parray

  2. CITH Sanatnagar, Srinagar, India

    Sumira Jan

  3. Centre of Research for Development, University of Kashmir, Srinagar, India

    Mohammad Yaseen Mir, Nowsheen Shameem & Azra N. Kamili

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  1. Javid A. Parray
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  2. Sumira Jan
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Correspondence to Javid A. Parray .

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  1. Faculty of Biology, National University of Uzbekistan, Tashkent, Uzbekistan

    Dilfuza Egamberdieva

  2. Department of Botany and Microbiology, King Saud University, Riyadh, Riyadh, Saudi Arabia

    Parvaiz Ahmad

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Parray, J.A., Jan, S., Mir, M.Y., Shameem, N., Kamili, A.N. (2018). Quorum Sensing: Melody Beneath the Ground. In: Egamberdieva, D., Ahmad, P. (eds) Plant Microbiome: Stress Response. Microorganisms for Sustainability, vol 5. Springer, Singapore. https://doi.org/10.1007/978-981-10-5514-0_9

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