Abstract
Ultrastructural studies help in understanding the tissue functions and aberrations at a cellular and subcellular level. It is carried out using electron microscopy: scanning electron microscopy or transmission electron microscopy. Very few studies have looked at the ultrastructural features for lacrimal drainage system. The current chapter would provide an overview of recent works in the lacrimal drainage system and the vast potential to do more in this area.
This is a preview of subscription content, log in via an institution.
References
Radnot M. Ultrastructure of the lacrimal sac. Ann Ophthalmol. 1972;4:1050–7.
Radnot M. The cilia of the lacrimal sac epithelium – SEM studies. Klin Monatsbl Augenheilkd. 1977;170:428–30.
Adenis JP, Loubet A, Leboutet MJ, et al. Ultrastructural aspect of different levels of the lacrimal system. J Fr Ophthalmol. 1980;3:343–8.
Adenis JP, Loubet A, Leboutet MJ, et al. Ultrastructural morphology at the different levels of the lacrimal passage mucosa. Arch Anat Cytol Pathol. 1980;28:371–5.
Radnot M. The fine structure of the oncocytes of the lacrimal sac. Klin Monatsbl Augenheilkd. 1981;179:249–50.
Thale A, Paulsen F, Rochels R, et al. Functional anatomy of the human efferent tear ducts: a new theory of tear outflow mechanism. Graefes Arch Clin Exp Ophthalmol. 1998;236:674–8.
Paulsen FP, Thale A, Hallmann UJ, et al. The cavernous body of human efferent tear ducts: function in tear outflow mechanism. Invest Ophthalmol Vis Sci. 2000;41:965–70.
Paulsen F. The human nasolacrimal ducts. Adv Anat Embryol Cell Biol. 2003;170:1–106.
Ali MJ, Baig F, Lakshman M, et al. Scanning electron microscopic features of the external and internal surfaces of normal adult lacrimal drainage system. Ophthal Plast Reconstr Surg. 2015;31:414–7.
Ali MJ, Mishra DK, Baig F, et al. Punctal stenosis: histopathology, immunology and electron microscopic features – a step towards unraveling the mysterious etiopathogenesis. Ophthal Plast Reconstr Surg. 2015;31:98–102.
Dave TV, Mohammed FA, Ali MJ, et al. Etiologic analysis of 100 failed anatomical dacryocystorhinostomies. Clin Ophthalmol. 2016;10:1419–22.
Ali MJ, Psaltis AJ, Wormald PJ. Long-term outcomes in revision powered endoscopic dacryocystorhinostomies. Int Forum Allergy Rhinol. 2014;4:1016–9.
Watelet JB, Bachert C, Gevaert P, et al. Wound healing of the nasal and paranasal mucosa: a review. Am J Rhinol. 2002;16:77–84.
Ali MJ, Mishra DK, Baig F, et al. Histopathology, immunohistochemistry, and electron microscopic features of a dacryocystorhinostomy ostium cicatrix. Ophthal Plast Reconstr Surg. 2016;32:333–6.
Xue K, Mellington FE, Norris JH. Meta-analysis of the adjunctive use of mitomycin C in primary and revision, external and endonasal dacryocystorhinostomy. Orbit. 2014;33:239–44.
Feng YF, Yu JG, Shi JL, et al. A meta-analysis of primary external dacryocystorhinostomy with and without mitomycin C. Ophthalmic Epidemiol. 2012;19:364–70.
Ali MJ, Mariappan I, Maddileti S, et al. Mitomycin C in dacryocystorhinostomy: the search for the right concentration and duration – a fundamental study on human nasal mucosa fibroblasts. Ophthal Plast Reconstr Surg. 2013;29:469–74.
Kumar V, Ali MJ, Ramachandran C. Effect of mitomycin-C on contraction and migration of human nasal mucosa fibroblasts: implications in dacryocystorhinostomy. Br J Ophthalmol. 2015;99:1295–300.
Nair AG, Ali MJ. Mitomycin-C in dacryocystorhinostomy: from experimentation to implementation and the road ahead: a review. Indian J Ophthalmol. 2015;63:335–9.
Kamal S, Ali MJ, Naik MN. Circumostial mitomycin C (COS-MMC) in external and endoscopic dacryocystorhinostomy: efficacy, safety profiles and outcomes. Ophthal Plast Reconstr Surg. 2014;30:187–90.
Singh M, Ali MJ, Naik MN. Long-term outcomes of circumostial injection of mitomycin C (COS-MMC) in dacryocystorhinostomy. Ophthal Plast Reconstr Surg. 2015;31:423–4.
Ali MJ, Baig F, Lakshman M, et al. Electron microscopic features of nasal mucosa treated with topical and circumostial injection of mitomycin C: implications in dacryocystorhinostomy. Ophthal Plast Reconstr Surg. 2015;31:103–7.
Unlu H, Aslan A, Toprak B, et al. Comparison of surgical outcomes in primary endoscopic dacryocystorhinostomy with and without silicone intubation. Ann Otol Rhinol Laryngol. 2002;111:704–9.
Feng YF, Cai JQ, Zhang JY, et al. A meta-analysis of primary dacryocystorhinostomy with and without silicone intubation. Can J Ophthalmol. 2011;46:521–7.
Moscato EE, Dolmetsch AM, Silkiss RZ, Seiff SR. Silicone intubation for the treatment of epiphora in adults with presumed functional nasolacrimal duct obstruction. Ophthal Plast Reconstr Surg. 2012;28:35–9.
Kim SE, Lee J, Lee SY. Clinical significance of the microbial growth on the surfaces of silicone tubes removed from dacryocystorhinostomy patients. Am J Ophthalmol. 2012;153:253–7.
Ali MJ, Manderwad G, Naik MN. The microbiological spectrum and antibiotic sensitivity profile of extubated silicone stents following dacryocystorhinostomy. Orbit. 2013;32:298–303.
Murphy J, Ali MJ, Psaltis AJ. Biofilm quantification on nasolacrimal silastic stents after dacryocystorhinostomy. Ophthal Plast Reconstr Surg. 2015;31:396–400.
Ramadan HH, Sanclemann JA, Thomas JG. Chronic rhinosinusitis and biofilms. Otolaryngol Head Neck Surg. 2005;132:414–7.
Samimi B, Bielory BP, Miller D, et al. Microbiological trends and biofilm growth on explanted periorbital biomaterials: a 30 year review. Ophthal Plast Reconstr Surg. 2013;29:376–81.
Ali MJ, Baig F, Lakshman M, et al. Biofilms and physical deposits on nasolacrimal silastic stents following dacryocystorhinostomy: is there a difference between ocular and nasal segments? Ophthal Plast Reconstr Surg. 2015;31:452–5.
Ali MJ, Baig F, Lakshman M, et al. Scanning electron microscopic features of extubated monoka stents. Ophthal Plast Reconstr Surg. 2017;33(2):90–2.
Ali MJ, Baig F, Naik MN. Electron microscopic features of intraluminal portion of nasolacrimal silastic stents following dacryocystorhinostomy. Is there a need for stents without a lumen? Ophthal Plast Reconstr Surg. 2016;32:252–6.
Ali MJ, Baig F, Lakshman M, et al. Scanning electron microscopic features of nasolacrimal silastic stents retained for prolong durations following dacryocystorhinostomy. Ophthal Plast Reconstr Surg. 2016;32:20–3.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Ali, M.J. (2018). Electron Microscopy of the Lacrimal System. In: Ali, M. (eds) Principles and Practice of Lacrimal Surgery. Springer, Singapore. https://doi.org/10.1007/978-981-10-5442-6_42
Download citation
DOI: https://doi.org/10.1007/978-981-10-5442-6_42
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-10-5441-9
Online ISBN: 978-981-10-5442-6
eBook Packages: MedicineMedicine (R0)