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Paravalvular Leakage After Transcatheter Aortic Valve Implantation

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Abstract

Transcatheter aortic valve implantation (TAVI) is the treatment of choice for inoperable or high-risk patients with severe aortic stenosis and is now expanding to intermediate- and low-risk patients [1–3]. A frequently seen complication after TAVI is paravalvular leakage (PVL), which is considered the Achilles’ heel of TAVI since several studies have shown an association with worse outcome [4–6]. Several trials and registries reported PVL rates ranging from 40% to 67% for trivial-mild leaks and from 7% to 20% for moderate-severe leaks [1, 7]. The wide variability of these frequencies may be partly related to the transcatheter heart valve (THV) design but may also reflect different methodologies for PVL assessment. Accurate PVL quantification remains challenging since there is no standardized method yet.

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Authors and Affiliations

  1. Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands

    Zouhair Rahhab M.D.

  2. Department of Interventional Cardiology, Thoraxcenter, ErasmusMC, Room Bd 171 ‘s Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands

    Nicolas M. Van Mieghem M.D., Ph.D.

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  1. Zouhair Rahhab M.D.
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Correspondence to Nicolas M. Van Mieghem M.D., Ph.D. .

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Editors and Affiliations

  1. Department of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland

    Grzegorz Smolka

  2. Department of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland

    Wojciech Wojakowski

  3. Department of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland

    Michal Tendera

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Rahhab, Z., Van Mieghem, N.M. (2017). Paravalvular Leakage After Transcatheter Aortic Valve Implantation. In: Smolka, G., Wojakowski, W., Tendera, M. (eds) Transcatheter Paravalvular Leak Closure. Springer, Singapore. https://doi.org/10.1007/978-981-10-5400-6_9

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