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Biomaterial-Based Microfluidics for Cell Culture and Analysis

Chapter
Part of the Integrated Analytical Systems book series (ANASYS)

Abstract

Microfluidic devices can integrate drug injection, bioreactors, sample separation and detection on a individual platform with properties of fluidic incubation, programmable three-dimensional (3D) channels in micro scale, low reagent consumption, and on-line detection, which makes them popular in in vitro cell culture and analysis. Since the appearance of the initial generation of microfluidics in 1970s, materials for microfluidics experienced the age of inorganics such as silicon and glasses, and now have entered the period of organics, in which main materials used in microfluidics are polymers. Also, polymers constructed the chips gradually undertake much more functions rather than a basic supporting plane through applying functional and smart biomaterials. In this chapter, biomaterials utilized in microfluidics will be elaborated from the perspectives of the fabrication of microfluidics, cell culture and analysis on chips.

Keywords

Biomaterials Microfluidic chip Cell culture Scaffolds Cell analysis Cell observation 

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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.Department of ChemistryTsinghua UniversityBeijingPeople’s Republic of China

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