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Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill pp 265–275Cite as

Antibiotic Stewardship in the Intensive Care Unit

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Abstract

Antimicrobial resistance (AMR) is a global patient safety challenge. The development of AMR is inevitable, but the overuse and misuse of antimicrobials has accelerated this process. Of particular concern is the rise in multidrug-resistant Gram-negative organisms. The challenge faced by many practitioners is to balance the immediate prudent use of antimicrobials at the individual sick patient level, against the wider but seemingly more distant threat of AMR. This chapter will set out the goals and principles of an antimicrobial stewardship program (ASP). It will discuss key components of a typical program in specific relation to intensive care and look at applicability on the shop floor and what the future might hold in this area.

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Author information

Authors and Affiliations

  1. Imperial College Healthcare NHS Trust, London, UK

    M. Gilchrist, E. T. Brannigan & G. Satta

  2. St George’s University Hospitals NHS Foundation Trust, London, UK

    M. Laundy

Authors
  1. M. Gilchrist
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  2. E. T. Brannigan
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  3. G. Satta
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  4. M. Laundy
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Corresponding author

Correspondence to M. Gilchrist .

Editor information

Editors and Affiliations

  1. Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia

    Andrew A. Udy

  2. Burns, Trauma and Critical Care Research Centre, The University of Queensland, Herston, Queensland, Australia

    Jason A. Roberts

  3. Burns, Trauma and Critical Care Research Centre, The University of Queensland, Herston, Queensland, Australia

    Jeffrey Lipman

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© 2018 Springer Nature Singapore Pte Ltd.

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Gilchrist, M., Brannigan, E.T., Satta, G., Laundy, M. (2018). Antibiotic Stewardship in the Intensive Care Unit. In: Udy, A., Roberts, J., Lipman, J. (eds) Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill. Adis, Singapore. https://doi.org/10.1007/978-981-10-5336-8_13

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  • DOI: https://doi.org/10.1007/978-981-10-5336-8_13

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  • Publisher Name: Adis, Singapore

  • Print ISBN: 978-981-10-5335-1

  • Online ISBN: 978-981-10-5336-8

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