Abstract
The absorption, distribution, metabolism, elimination and toxicity (ADMET) are important aspects of drug molecules. This chapter covers the physicochemical properties of drugs, the pH and solubility, and the approaches to improving aqueous solubility as well as the drug metabolism and drug/drug interactions, followed by recent development on databases particularly related to the ADMET profiling and prediction.
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Zhong, H.A. (2017). ADMET Properties: Overview and Current Topics. In: Grover, A. (eds) Drug Design: Principles and Applications. Springer, Singapore. https://doi.org/10.1007/978-981-10-5187-6_8
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DOI: https://doi.org/10.1007/978-981-10-5187-6_8
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