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Determination of the Effect of SiO2 Nanoparticles on Spontaneous Activity of Rat Uterus Smooth Muscles using Wavelet Scalogram Analysis

  • Conference paper
  • First Online:
EMBEC & NBC 2017 (EMBEC 2017, NBC 2017)

Part of the book series: IFMBE Proceedings ((IFMBE,volume 65))

  • 36 Accesses

Abstract

Today, nanomaterials are used in many industrial areas such as electronics, optics, textiles, as well as in medical devices, biosensors, etc. Among various types of nanoparticles (NPs), silica nanoparticles (SiO2 NPs) are one of the most used NPs, especially in nanostructuring, drug delivery, cosmetic and optical imaging agents. Although NPs have a great importance in nanotechnology, they also have a potential toxic effect, which cause health problems. Uterus is a hollow muscular organ situated deep within the female pelvic cavity. The uterine smooth muscle, which is situated in uterus, is able to produce regular spontaneous contractions without any hormonal or nervous input [17]. Uterine contractions are important in many reproductive functions including the transport of sperms and embryo, menstruation, pregnancy and parturition. In this study, the effect of SiO2 NPs on uterine contractions are investigated. Experimentally recorded spontaneous activity of uterus are analyzed using wavelet transform. Obtained results show that, increasing doses of SiO2 NPs decrease the contraction frequency significantly, while energy of contractions does not change considerably.

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Author information

Authors and Affiliations

  1. Faculty of Medicine, Department of Biophysics, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Türkiye

    Selma Yaman

  2. Faculty of Medicine, Department of Biophysics, Mersin University, Mersin, Türkiye

    Ülkü Çömelekoğlu

  3. Faculty of Engineering, Department of Electrical-Electronics Engineering, Mersin University, Mersin, Türkiye

    Evren Değirmenci

Authors
  1. Selma Yaman
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  2. Ülkü Çömelekoğlu
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  3. Evren Değirmenci
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Correspondence to Evren Değirmenci .

Editor information

Editors and Affiliations

  1. Tampere University of Technology, BioMediTech Institute and Faculty of Biomedical Science and Engineering, Tampere, Finland

    Hannu Eskola

  2. Tampere University of Technology, BioMediTech Institute and Faculty of Biomedical Science and Engineering, Tampere, Etelä-Suomi, Finland

    Outi Väisänen

  3. Tampere University of Technology, BioMediTech Institute and Faculty of Biomedical Science and Engineering, Tampere, Etelä-Suomi, Finland

    Jari Viik

  4. Tampere University of Technology, BioMediTech Institute and Faculty of Biomedical Science and Engineering, Tampere, Etelä-Suomi, Finland

    Jari Hyttinen

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Yaman, S., Çömelekoğlu, Ü., Değirmenci, E. (2018). Determination of the Effect of SiO2 Nanoparticles on Spontaneous Activity of Rat Uterus Smooth Muscles using Wavelet Scalogram Analysis. In: Eskola, H., Väisänen, O., Viik, J., Hyttinen, J. (eds) EMBEC & NBC 2017. EMBEC NBC 2017 2017. IFMBE Proceedings, vol 65. Springer, Singapore. https://doi.org/10.1007/978-981-10-5122-7_30

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  • DOI: https://doi.org/10.1007/978-981-10-5122-7_30

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-5121-0

  • Online ISBN: 978-981-10-5122-7

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