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Sensitivity Distribution of Electrical Impedance Epithelial Measurement Systems

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EMBEC & NBC 2017 (EMBEC 2017, NBC 2017)

Part of the book series: IFMBE Proceedings ((IFMBE,volume 65))

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Abstract

Epithelia are essential tissues that separate body compartments from each other and are affected by a plethora of diseases and conditions. Electrical properties are a convenient method to study the state of these tissues. There are various measurement setups for studying these properties. However, there has been no studies on how the setup of the electrodes affects the sensitivity distribution of the measurement system. We created a computational model of 4-electrode electrical impedance measurement system to study how the placement of the electrode as well as defects in the epithelium affect the sensitivity distribution. Our results show that the sensitivity is highly dependent on the frequency as well as on the distance between the electrodes and the epithelium. The sensitivity become more concentrated to areas between the electrodes when they were moved closer to the epithelium. The sensitivity should be taken into account when developing measurement systems to study localized phenomena with the electrodes placed close to the epithelium.

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Authors and Affiliations

  1. BioMediTech Institute and Faculty of Biomedical Sciences and Engineering, Tampere University of Technology, Tampere, Finland

    Aapo Tervonen & Jari Hyttinen

Authors
  1. Aapo Tervonen
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  2. Jari Hyttinen
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Corresponding author

Correspondence to Aapo Tervonen .

Editor information

Editors and Affiliations

  1. Tampere University of Technology, BioMediTech Institute and Faculty of Biomedical Science and Engineering, Tampere, Finland

    Hannu Eskola

  2. Tampere University of Technology, BioMediTech Institute and Faculty of Biomedical Science and Engineering, Tampere, Etelä-Suomi, Finland

    Outi Väisänen

  3. Tampere University of Technology, BioMediTech Institute and Faculty of Biomedical Science and Engineering, Tampere, Etelä-Suomi, Finland

    Jari Viik

  4. Tampere University of Technology, BioMediTech Institute and Faculty of Biomedical Science and Engineering, Tampere, Etelä-Suomi, Finland

    Jari Hyttinen

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Tervonen, A., Hyttinen, J. (2018). Sensitivity Distribution of Electrical Impedance Epithelial Measurement Systems. In: Eskola, H., Väisänen, O., Viik, J., Hyttinen, J. (eds) EMBEC & NBC 2017. EMBEC NBC 2017 2017. IFMBE Proceedings, vol 65. Springer, Singapore. https://doi.org/10.1007/978-981-10-5122-7_156

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  • DOI: https://doi.org/10.1007/978-981-10-5122-7_156

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-5121-0

  • Online ISBN: 978-981-10-5122-7

  • eBook Packages: EngineeringEngineering (R0)

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