Abstract
Needling manipulation can evoke consistently increased signal changes across several different brain regions as well as evoke more complex and time-varied neural responses during the poststimulus phase. Acupuncture creates a biphasic response consisting of an initial phase involving effects due to needle stimulation of deep tissue, with skin piercing and biochemical reactions to tissue damage, followed by a second phase comprising prolonged physiological effects for a period after the removal of the acupuncture needle. Stimulating different acupoints for treating various clinical conditions is usually accompanied by multidimensional physiological as well as psychological responses which are regulated by the CNS. This suggests that the peripheral acupoint-brain interaction may involve the coordinated activity of large-scale brain networks. The CNS encodes the body’s responses to peripheral stimulation at different acupoints which are then deciphered within a functionally specific brain network. Furthermore, the late, sustained response (the second phase described above) utilizes these brain networks to implement certain long-term functions.
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Bai, L., Tian, J. (2018). Temporospatial Encoding of Acupuncture Effects in the Brain. In: Tian, J. (eds) Multi-Modality Neuroimaging Study on Neurobiological Mechanisms of Acupuncture. Springer, Singapore. https://doi.org/10.1007/978-981-10-4914-9_2
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