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Design, Fabrication, and Modification Protocols of Functional Micro-/Nanoimaging Probes

  • Doudou Wang
  • Li LiuEmail author
  • Wei Ma
  • Daren Liu
  • Qiuming Su
  • Xuemei Gu
  • Gaoyi Yang
  • Zhe Liu
Chapter
Part of the Engineering Materials book series (ENG.MAT.)

Abstract

The biosafety of micro-/nanoimaging probes is one of the most important elements that should be taken into consideration before their design and fabrication. In order to endow them specificity to lesions and bioavailability in vivo, targeting biomolecules, optimized biodistribution, and acceptable biocompatibility need to be introduced. These prerequisites ensure their behavior in the body and pave the way for their ultimate medical applications in humans, which should be pursued throughout the development of molecular imaging probes.

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Copyright information

©  Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Doudou Wang
    • 1
  • Li Liu
    • 2
    • 3
    Email author
  • Wei Ma
    • 4
  • Daren Liu
    • 5
  • Qiuming Su
    • 6
  • Xuemei Gu
    • 7
  • Gaoyi Yang
    • 8
  • Zhe Liu
    • 9
    • 11
    • 10
    • 12
  1. 1.Wenzhou Medical UniversityWenzhouPeople’s Republic of China
  2. 2.Institute of Chemistry, Chinese Academy of SciencesBeijingPeople’s Republic of China
  3. 3.Beijing National Laboratory for Molecular SciencesBeijingPeople’s Republic of China
  4. 4.Institute for Materials Chemistry and Engineering (IMCE), Kyushu UniversityFukuokaJapan
  5. 5.The Second Affiliated Hospital of Zhejiang UniversityHangzhouPeople’s Republic of China
  6. 6.School of MedicineZhejiang UniversityHangzhouPeople’s Republic of China
  7. 7.The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouPeople’s Republic of China
  8. 8.Hangzhou Red Cross HospitalHangzhouPeople’s Republic of China
  9. 9.Academy of Medical Engineering and Translational MedicineTianjin UniversityTianjinPeople’s Republic of China
  10. 10.The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhouPeople’s Republic of China
  11. 11.Wenzhou Institute of Biomaterials and EngineeringChinese Academy of SciencesWenzhouPeople’s Republic of China
  12. 12.Wenzhou Institute of Biomaterials and EngineeringWenzhou Medical UniversityWenzhouPeople’s Republic of China

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