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Peripartum Cardiomyopathy: Do Exosomes Play a Role?

  • Huanyu Gu
  • Qiying Dai
  • Zhuyuan Liu
  • Hongbao Wang
  • Jianhua YaoEmail author
  • Lei ZhouEmail author
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 998)

Abstract

Peripartum cardiomyopathy (PPCM) refers to irreversible cardiomyocyte damage that occurs during the last month of pregnancy, or within 5 months after giving birth. It is characterized by systolic heart failure. This life-threatening condition is relatively uncommon, but the incidence has been climbing up. Because of its high mortality, it is crucial for physicians to have high suspicious for the disease. Studies have been done to search into specific lab test and treatment for PPCM. Therapies like anti-viral, anti-inflammatory and immunosuppression regimen have been explored. New regimen like exosomes has also been explored and revealed promising effects.

Keywords

Peripartum cardiomyopathy Exosome 

Notes

Acknowledgements

This work was supported by the grants from National Natural Science Foundation of China (81370280 and 81570332), the grant from Yangpu Commission of Science and Technology Commission, and Yangpu Commission of Health and Family Planning (YP15M07), and the “Chenguang Program” supported by Yangpu Hospital, Tongji University School of Medicine (Ye1201409).

Competing Financial Interests The authors declare no competing financial interests.

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© Springer Nature Singapore Pte Ltd. 2017

Authors and Affiliations

  1. 1.Department of CardiologyFirst Affiliated Hospital of Nanjing Medical UniversityNanjingChina
  2. 2.Metrowest Medical CenterFraminghamUSA
  3. 3.Department of CardiologyYangpu Hospital, Tongji University School of MedicineShanghaiChina

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