Abstract
Blood pulse waveform relates to the physical properties of the circulatory system, and carries valuable hemodynamic information for the management of cardiovascular patients. In this paper, we present a modeling technique to reconstruct and characterize the cardiac-related pulse waves, observed in laser Doppler flowmetry signals of the peripheral skin perfusion. We tested the sensitivity of the proposed model to physiological alterations of the vascular system, investigating the effect of ageing on a set of parameters describing the reconstructed pulse waves. Waveform data collected from a set of 56 subjects demonstrate the existence of a significant correlation between ageing and the shape of the peripheral perfusion pulse waves, and indicate a possible relationship with the mechanical properties of the vascular tree.
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References
Alastruey, J., Parker, K.H., Sherwin, S.J.: Arterial pulse wave haemodynamics.In: 11th International Conference on Pressure Surges. pp. 401–442. VirtualPiE Led t/a BHR Group (2012)
Dart, A.M., Kingwell, B.A.: Pulse pressure – a review of mechanisms andclinical relevance. Journal of the American College of Cardiology 37(4),975–984 (2001)
Vlachopoulos, C., Aznaouridis, K., Stefanadis, C.: Prediction of cardiovascularevents and all-cause mortality with arterial stiffness: a systematic reviewand meta-analysis. Journal of the American College of Cardiology 55(13),1318–1327 (2010)
Humeau, A., Steenbergen, W., Nilsson, H., Strömberg, T.: Laser dopplerperfusion monitoring and imaging: novel approaches. Medical & biologicalengineering & computing 45(5), 421–435 (2007)
Bocchi, L., Evangelisti, A., Barrella, M., Bevilacqua, M.: Shape analysis ofthe microcirculatory flow wave. Physiological measurement 36(10),2147–2158 (2015)
Charkoudian, N.: Skin blood flow in adult human thermoregulation: how it works,when it does not, and why. Mayo Clin Proc 78(5), 603–612 (2003)
Cracowski, J.L., Minson, C.T., Salvat-Melis, M., Halliwill, J.R.:Methodological issues in the assessment of skin microvascular endothelialfunction in humans. Trends in pharmacological sciences 27(9), 503–508(2006)
Moré, J.J.: The levenberg-marquardt algorithm: implementation and theory.In: Numerical analysis, pp. 105–116. Springer (1978)
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Sorelli, M., Perrella, A., Bocchi, L. (2017). Cardiac pulse waves modeling and analysis in laser Doppler perfusion signals of the skin microcirculation . In: Badnjevic, A. (eds) CMBEBIH 2017. IFMBE Proceedings, vol 62. Springer, Singapore. https://doi.org/10.1007/978-981-10-4166-2_4
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DOI: https://doi.org/10.1007/978-981-10-4166-2_4
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