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Helicobacter pylori (H. pylori) Eradication

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Autoimmune Thrombocytopenia

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Abstract

In 1998, Gasbarrini et al. reported that eradication therapy for Helicobacter pylori (H. pylori) increased platelet counts in most H. pylori-positive immune thrombocytopenia (ITP) patients. A large number of retrospective and prospective studies have since been performed in order to evaluate the efficacy of eradication therapy. A positive relationship was reported between ITP and H. pylori infection, and the eradication of H. pylori resulted in a significant increase in platelet counts in more than 50% of eradication-successful ITP cases. These results suggest that H. pylori infection is involved in the mechanisms underlying thrombocytopenia.

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Authors and Affiliations

  1. Department of Clinical Research, Hiroshima-Nishi Medical Center, Hiroshima, Japan

    Toshiro Takafuta M.D., Ph.D.

  2. Department of Nursing, Yasuda Women’s University, Hiroshima, Japan

    Kingo Fujimura M.D., Ph.D.

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  1. Toshiro Takafuta M.D., Ph.D.
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  2. Kingo Fujimura M.D., Ph.D.
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Correspondence to Toshiro Takafuta M.D., Ph.D. .

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Editors and Affiliations

  1. Division of Hematology and Oncology Department of Internal Medicine, Iwate Medical University School of Medicine, Morioka, Iwate, Japan

    Yoji Ishida

  2. Department of Blood Transfusion, Osaka University Hospital, Suita, Osaka, Japan

    Yoshiaki Tomiyama

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Takafuta, T., Fujimura, K. (2017). Helicobacter pylori (H. pylori) Eradication. In: Ishida, Y., Tomiyama, Y. (eds) Autoimmune Thrombocytopenia　. Springer, Singapore. https://doi.org/10.1007/978-981-10-4142-6_12

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  • DOI: https://doi.org/10.1007/978-981-10-4142-6_12

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