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Scaffolds Reinforced by Fibers or Tubes for Hard Tissue Repair

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Tissue Repair

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Abstract

Formed by biological mineralization, hard tissues not only play a supporting role in vivo, but also contribute to the protection of internal organs. Currently, hard tissue defects have already become a type of common disease owing to fracture, trauma, pathological biomineralization or degeneration, etc. It has been well recognized that scaffolds reinforced by fibers or tubes can overcome the shortages of traditional tissue grafts to repair hard tissues. However, to achieve satisfactory scaffolds, their composition, physicochemical properties, biodegradability, biocompatibility and bioactivity should be comprehensively studied. In this chapter, we mainly introduce those properties and their influential factors of scaffolds reinforced by fibers or tubes, mainly focusing on special design and fabrication of novel satisfactory scaffolds reinforced by fibers or tubes for hard tissue repair, and how the addition of fibers or tubes affects the special functions in vitro and in vivo, which suggests that the reinforcement using fibers or tubes can enhance significantly hard tissue repair or regeneration efficacy, and should be one promising means to develop new high-performanced scaffolds for hard tissue repair.

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  1. Jianrong Wei, Tianxiao Zhao and Jie Liao contributed equally to this work.

Authors and Affiliations

  1. Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China

    Jianrong Wei, Tianxiao Zhao, Jie Liao, Yan Liu, Linhao Li & Xiaoming Li

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  1. Jianrong Wei
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  2. Tianxiao Zhao
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  3. Jie Liao
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  4. Yan Liu
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  6. Xiaoming Li
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Correspondence to Xiaoming Li .

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  1. Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, China

    Xiaoming Li

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Wei, J., Zhao, T., Liao, J., Liu, Y., Li, L., Li, X. (2017). Scaffolds Reinforced by Fibers or Tubes for Hard Tissue Repair. In: Li, X. (eds) Tissue Repair . Springer, Singapore. https://doi.org/10.1007/978-981-10-3554-8_7

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