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New Horizons of Process Chemistry pp 147–162Cite as

Methylenation Reaction of Carbonyl Compounds Using Julia-Kocienski Reagents

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Abstract

Methylenation of carbonyl compounds is an important reaction in organic synthesis. In this mini-review, typical and most often used methylenation reactions are summarized briefly. The new Julia-Kocienski type methylenation reagents are fully summarized together with its reaction mechanism and applications to the total synthesis of natural products.

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Acknowledgements

This work was partially supported financially by the JSPS KAKENHI Grant Number 25410111.

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Authors and Affiliations

  1. Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Yanagido 1-1, Gifu, 501-1193, Japan

    Kaori Ando

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  1. Kaori Ando
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Correspondence to Kaori Ando .

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Editors and Affiliations

  1. Doshisha Women's College of Liberal Arts , Kyotanabe, Japan

    Kiyoshi Tomioka

  2. Meijo University, Nagoya, Japan

    Takayuki Shioiri

  3. Gifu Pharmaceutical University , Gifu, Japan

    Hironao Sajiki

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© 2017 Springer Nature Singapore Pte Ltd.

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Ando, K. (2017). Methylenation Reaction of Carbonyl Compounds Using Julia-Kocienski Reagents. In: Tomioka, K., Shioiri, T., Sajiki, H. (eds) New Horizons of Process Chemistry. Springer, Singapore. https://doi.org/10.1007/978-981-10-3421-3_11

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