Tissue Engineering and Oncological Surgery

Abstract

The repair and functional reconstruction of tissue and organ defects after tumor resection are a major difficult problem currently faced by the oncological surgery. Except that some defects with a small area don’t require special treatment, all defects with a large area require to be repaired with the transplantation of autologous or allogeneic tissues and organs. The autologous transplantation has the disadvantage that the wound repair causes a new wound, and the allogeneic transplantation has some disadvantages that the donor source is insufficient and there is the immunological rejection. For a long time, people have been dreaming that the body’s tissues and organs can be produced on a large scale in the factory just like the machine parts; once the body’s tissues and organs have problems, they can be replaced with new parts. The proposition, establishment, and development of tissue engineering provide the possibility to achieve this dream; a small amount of seed cells after in vitro amplification are compounded with biological materials to construct new tissues or organs, which are used to replace and repair the affected and defected tissues and organs and recover the physiological functions [1].