Abstract
We delineate feasibility of computational clinical trial platform for therapy optimization approach to neuroprotection and neurorestoration in cerebrovascular accident or intracranial injury. Cell kinetics or drug response characteristics is quantified by systems biology model that is validated based on experimental findings of animal and human study. Platform is built on the Government’s high-speed NKN system, connecting medical centres across the country.
S. Kapoor, V. Pareek, V.P. Subramanyam Rallabandi—Equal contribution.
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Acknowledgments
The work of PKR, SK, VP and VPSR were respectively supported by Govt. of India’s Dept. of Biotechnology, DBT (Glue Grant scheme and HRD scheme), Dept. of Electronics & Information Technology (Spatiotemporal mapping project), and Defense Research & Development Organization.
The cooperation of Alan Evans and Samir Das, McGill University, is greatly appreciated. Support for the logistics of the work is thankfully solicited from Tata Innovation Program, DBT, and Office of Principal Science Adviser, National Knowledge Network, Government of India.
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Roy, P.K., Kapoor, S., Pareek, V., Subramanyam Rallabandi, V.P. (2017). Therapeutic Platforms for Ischemic and Traumatic Brain Injuries Across National-Level Neuroimaging Grids. In: Shorey, R., Ghosh, P. (eds) Healthcare Engineering. Springer, Singapore. https://doi.org/10.1007/978-981-10-3111-3_3
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DOI: https://doi.org/10.1007/978-981-10-3111-3_3
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