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Microstructure and Composition Dependent Physical and Cytocompatibility Property of Glass-Ceramics for Dental Restoration

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Book cover Biomaterials for Musculoskeletal Regeneration

Part of the book series: Indian Institute of Metals Series ((IIMS))

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Abstract

The design and development of glass ceramic materials provide us the unique opportunity to study the microstructure development with changes in either base glass composition or heat treatment conditions and thereby developing an understanding of processing-microstructure-property (mechanical/biological) relationship. Among various brittle materials, the mica based glass ceramics with crystalline ceramic embedded in a glass matrix are of greater scientific interest, because of their machinability . Considering the potential of these materials as dental implants, this chapter summaries the published results on K2O–B2O3–Al2O3–SiO2–MgO–F glass ceramics to demonstrate the microstructure dependent mechanical, tribological and cytocompatibility properties. Among the high hardness of around 8 GPa together with 3-point flexural strength and elastic modulus of 80 MPa and 69 GPa, respectively were obtained in glass ceramics with maximum amount of crystals. While analyzing influence of environment on the friction and wear behavior systematic decrease in wear rate with test duration was recorded with a minimum wear rate of 10−5 mm3/Nm after 100,000 fretting cycles in artificial saliva . The in vitro results illustrate how small variation in fluorine and boron in base glass composition influences significantly the cytocompatibility and antimicrobial bactericidal property, as evaluated using a range of biochemical assays. Overall, the mechanical, tribological property, in vitro cytocompatibility study, when taken together clearly reveals that microstructure and base glass composition play an important role in enhancing the cellular functionality and antimicrobial property.

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Authors and Affiliations

  1. Indian Institute of Science, Bangalore, Karnataka, India

    Bikramjit Basu

  2. Indian Institute of Technology Delhi, New Delhi, Delhi, India

    Sourabh Ghosh

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Correspondence to Sourabh Ghosh .

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Basu, B., Ghosh, S. (2017). Microstructure and Composition Dependent Physical and Cytocompatibility Property of Glass-Ceramics for Dental Restoration. In: Biomaterials for Musculoskeletal Regeneration. Indian Institute of Metals Series. Springer, Singapore. https://doi.org/10.1007/978-981-10-3017-8_5

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