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Case Study: Development of Constructs for Maxillofacial Reconstruction

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Biomaterials for Musculoskeletal Regeneration

Part of the book series: Indian Institute of Metals Series ((IIMS))

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Abstract

Increasing number of clinical incidences of maxillofacial disorders has developed the quest for the fabrication of improved synthetic materials to aid in complete craniofacial restoration. Replicating the complex 3D architecture and functional dynamics of maxillofacial bone tissue is a challenging proposition which aggravates the need for a custom-made, on demand tissue replacement strategy for rendering patient specificity which could not be achieved till date. Textile technology offers versatility to develop 3D spatial structures with tailor-made mechanical properties in the order of micro- and macro meters. 3D printed structures have fascinating potential for reconstruction of maxillofacial deformations due to the ability to fabricate patient-specific, defect site-specific structural features in the order of several nanometers along with the flexibility of being tailored into any desired shape or size. These case studies highlight clinical trials to evaluate the key properties of high performance textile braided structures for preservation of dimension of alveolar ridge as well as 3D printed Hydroxyapatite Direct-write scaffolds for maxillofacial reconstruction and how tailoring their architecture could enhance patient-specificity and defect-specificity in situ.

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  1. Indian Institute of Science, Bangalore, Karnataka, India

    Bikramjit Basu

  2. Indian Institute of Technology Delhi, New Delhi, Delhi, India

    Sourabh Ghosh

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Correspondence to Sourabh Ghosh .

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Basu, B., Ghosh, S. (2017). Case Study: Development of Constructs for Maxillofacial Reconstruction. In: Biomaterials for Musculoskeletal Regeneration. Indian Institute of Metals Series. Springer, Singapore. https://doi.org/10.1007/978-981-10-3017-8_10

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