Abstract
While invasive coronary angiography (CAG) has been considered the diagnostic standard for evaluating patients with suspected or known coronary artery disease (CAD), adjunctive evaluations are proposed because of its inability to determine functional significance of coronary stenosis despite the importance of objective evidence of ischemia to improve patients’ symptoms and outcomes [1–3]. Advances in intracoronary physiologic measurements allowed interventional cardiologists to have useful information to determine treatment strategies for patients with CAD. The cost-effectiveness is also improved when coronary physiology is used to guide coronary revascularization compared with that guided by CAG alone [4–7]. In particular, fractional flow reserve (FFR) by pressure-wire technology has been confirmed to provide useful guidance for determining treatment strategy in various clinical subsets of patients and coronary lesions and is recommended by current guidelines to detect ischemia-producing lesions after diagnostic CAG when objective evidence of inducible ischemia is not available [8–11]. Recently, as more refined methods for invasively determining the functional significance of CAD have been developed and are being extensively tested, interest in coronary physiology has been renewed and increasing. In this chapter, we review and summarize the main characteristics of other invasive functional indices of epicardial segment of coronary circulatory system, besides FFR.
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Lim, HS., Yang, HM. (2018). Other Physiologic Indices for Epicardial Stenosis. In: Hong, MK. (eds) Coronary Imaging and Physiology. Springer, Singapore. https://doi.org/10.1007/978-981-10-2787-1_24
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DOI: https://doi.org/10.1007/978-981-10-2787-1_24
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