Abstract
To those who acquired their anatomical knowledge of the skeleton with the aid of clean, dried bone specimens or a plastic mannequin, it may appear as a mere inert weight-bearing scaffold of the human body. However, like all other organs, the bone constantly undergoes remodeling and tubulation through the physiological and metabolic activities of osteoblasts and osteoclasts. The principal role played by these bone cells is the maintenance of bone integrity and calcium homeostasis by balancing between the ratio of bone collagen production and resorption and by governing mineralization processes. Collagen production is a histological property common to various connective tissues, but mineralization is unique to bone cells.
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Bahk, YW. (2017). Introduction and Fundamentals of Pinhole Scintigraphy. In: Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-10-2759-8_1
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