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Modulation of Wnt/β-Catenin Signaling by Chemoprevention

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Cancer and Chemoprevention: An Overview

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Abstract

More than 100 years ago, this theory that natural compounds might impede cancer development was stated and the effect of small natural compounds obtained from plants and fungi was examined on tumor development and growth in various laboratories. Presently, many labs are working to check the efficacy of these small molecules in modulating various signaling pathways and regulations of basic cellular functions like cell proliferation, cell differentiation, and apoptosis. Hence upgrading the current knowledge and deciphering the molecular mechanisms that underlie the action of these small molecules, thereby, provide clear understanding of signaling pathways in healthy and pathological states (Lustig and Behrens 2003; Nathália et al. 2014; Phelps et al. 2009).

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  1. Department of Toxicology, Jamia Hamdard, New Delhi, India

    Summya Rashid

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Rashid, S. (2017). Modulation of Wnt/β-Catenin Signaling by Chemoprevention. In: Cancer and Chemoprevention: An Overview. Springer, Singapore. https://doi.org/10.1007/978-981-10-2579-2_13

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