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GI Surgery Annual pp 1–14Cite as

Recent Advances in Oesophageal Adenocarcinoma

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Part of the book series: GI Surgery Annual ((GISA,volume 22))

Abstract

The incidence of oesophageal adenocarcinoma (EAC) has risen sharply by 400 % over the past two decades in the western world [1]. Barrett’s oesophagus (BE) is believed to be the precursor lesion for EAC. EAC develops via the metaplasia–dysplasia–carcinoma sequence as a consequence of long standing gastro-oesophageal reflux disease (GERD). Caucasian race and male gender are associated with a greatly increased risk of EAC [2]. GERD, obesity, smoking and H. pylori treatment have been implicated as risk factors for the development of EAC [3]. Over the past decade several advances have been made in the assessment and management of BE and EAC. We briefly summarize the same.

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Author information

Authors and Affiliations

  1. Department of Surgery, Creighton University School of Medicine, Omaha, NE, USA

    S. K. Mittal & P. K. Shah

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  1. S. K. Mittal
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  2. P. K. Shah
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Editor information

Editors and Affiliations

  1. Department of GI Surgery and Liver Transplantation, All India Institute of Medical Sciences, New Delhi, India

    Peush Sahni

  2. Department of GI Surgery and Liver Transplantation, All India Institute of Medical Sciences, New Delhi, India

    Sujoy Pal

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© 2015 T.K. Chattopadhyay

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Mittal, S.K., Shah, P.K. (2015). Recent Advances in Oesophageal Adenocarcinoma. In: Sahni, P., Pal, S. (eds) GI Surgery Annual. GI Surgery Annual, vol 22. Springer, Singapore. https://doi.org/10.1007/978-981-10-2010-0_1

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  • DOI: https://doi.org/10.1007/978-981-10-2010-0_1

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-2009-4

  • Online ISBN: 978-981-10-2010-0

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