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Inflammation: the Common Link in Brain Pathologies pp 1–16Cite as

Biology of Neuroinflammation: A Common Denominator in Brain Pathologies

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Abstract

Neuroinflammation is a common denominator of diverse neurological diseases. While acute inflammatory response is considered to be neuroprotective, chronic inflammation induces cascades of inflammatory reactions that leads to neurodegeneration. The harmful effect of chronic inflammation in modulating the course of disease has been well documented in a wide range of neurodegenerative disorders like Alzheimer’s disease, Huntington’s disease, Amyotrophic lateral sclerosis, etc., Overall goal of this review is to provide a broad description of the current state of knowledge of neuroinflammation associated with various acute and chronic neurological disorders.

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  1. National Research Professor, National Brain Research Centre, Manesar, India

    Prakash Narain Tandon

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  1. Molecular and Cellular Neuroscience, National Brain Research Centre, Gurgaon, Delhi, India

    Nihar Jana

  2. Molecular and Cellular Neuroscience, National Brain Research Centre, Gurgaon, Delhi, India

    Anirban Basu

  3. National Brain Research Centre, National Research Professor, National Brain Research Centre, Gurgaon, Delhi, India

    Prakash Narain Tandon

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Tandon, P.N. (2016). Biology of Neuroinflammation: A Common Denominator in Brain Pathologies. In: Jana, N., Basu, A., Tandon, P. (eds) Inflammation: the Common Link in Brain Pathologies. Springer, Singapore. https://doi.org/10.1007/978-981-10-1711-7_1

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