Abstract
This chapter presents the application of the information-thermodynamic theory based on the causal networks to the biochemical signal transduction. We discuss the role of thermodynamics of information processing in sensory adaptation such as the E. coli chemotaxis. We theoretically shows that the robustness of adaptation is thermodynamically bounded by the information flow inside the cell. We discuss the similarity and the difference between our thermodynamic result and the noisy-channel coding theorem in the classical information theory. We also numerically shows that the signal transduction of E. coli chemotaxis is efficient as an information-thermodynamic engine.
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References
S. Ito, T. Sagawa, Maxwell’s demon in biochemical signal transduction with feedback loop. Nature Communications 6, 7498 (2015)
R. Phillips, J. Kondev, J. Theriot, H. Garcia, Physical Biology of the Cell (Garland Science, New York, 2009)
B.D. Gomperts, I.M. Kramer, P.E. Tatham, Signal Transduction (Academic Press, Amsterdam, 2009)
N. Barkal, S. Leibler, Robustness in simple biochemical networks. Nature 387, 913 (1997)
G. Lan, P. Sartori, S. Neumann, V. Sourjik, Y. Tu, The energy-speed-accuracy trade-off in sensory adaptation. Nat. Phys. 8, 422–428 (2012)
U. Alon, M.G. Surette, N. Barkai, S. Leibler, Robustness in bacterial chemotaxis. Nature 397, 168 (1999)
E. Korobkova, T. Emonet, J.M. Vilar, T.S. Shimizu, P. Cluzel, From molecular noise to behavioural variability in a single bacterium. Nature 428, 574–578 (2004)
P. Sartori, Y. Tu, Noise filtering strategies in adaptive biochemical signaling networks. J. Stat. Phys. 142, 1206–1217 (2011)
Y. Tu, T.S. Shimizu, H.C. Berg, Modeling the chemotactic response of Escherichia coli to time-varying stimuli. Proc. Natl. Acad. Sci. USA 105, 14855–14860 (2008)
F. Tostevin, P.R. ten Wolde, Mutual information between input and output trajectories of biochemical networks. Phys. Rev. Lett. 102, 218101 (2009)
Y. Tu, The nonequilibrium mechanism for ultrasensitivity in a biological switch: sensing by Maxwell’s demons. Proc. Natl. Acad. Sci. USA 105, 11737–11741 (2008)
K. Sekimoto, Stochastic Energetics (Springer, New York, 2010)
U. Seifert, Stochastic thermodynamics, fluctuation theorems and molecular machines. Rep. Prog. Phys. 75, 126001 (2012)
T.M. Cover, J.A. Thomas, Elements of Information Theory (Wiley, New York, 1991)
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© 2016 Springer Science+Business Media Singapore
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Ito, S. (2016). Application to Biochemical Signal Transduction. In: Information Thermodynamics on Causal Networks and its Application to Biochemical Signal Transduction. Springer Theses. Springer, Singapore. https://doi.org/10.1007/978-981-10-1664-6_7
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DOI: https://doi.org/10.1007/978-981-10-1664-6_7
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Online ISBN: 978-981-10-1664-6
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