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Viral Noncoding RNAs in Cancer Biology

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The Long and Short Non-coding RNAs in Cancer Biology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 927))

Abstract

Over 12 % of all human cancers are caused by oncoviruses, primarily including Epstein–Barr virus (EBV), high-risk human papillomaviruses (HPVs), hepatitis B and C viruses (HBV and HCV, respectively), and Kaposi’s sarcoma herpesvirus (KSHV). In addition to viral oncoproteins, a variety of noncoding RNAs (ncRNAs) produced by oncoviruses have been recognized as important cofactors that contribute to the oncogenic events. In this chapter, we will focus on the recent understanding of the long and short noncoding RNAs, as well as microRNAs of the viruses, and discuss their roles in the biology of multistep oncogenesis mediated by established human oncoviruses.

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Acknowledgments

This work was partly supported by the National Natural Science Foundation of China (81172188, 91129709), the National Key Basic Research Program, and the National Key Technologies R&D Program of the Ministry of Science and Technology, China (2013CB967203, 2013BAI01B07).

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Authors and Affiliations

  1. Center for Molecular Medicine of Xiangya Hospital, Collaborative Innovation Center for Cancer Medicine, Central South University, Changsha, Hunan, 410008, China

    Zhi Li, Shujun Fu & Lun-Quan Sun

  2. Key Laboratory of Molecular Radiation Oncology, Hunan, China

    Zhi Li, Shujun Fu & Lun-Quan Sun

  3. Research Center for Technologies of Nucleic Acid-Based Diagnostics and Therapeutics, Hunan, China

    Zhi Li, Shujun Fu & Lun-Quan Sun

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  1. Zhi Li
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  2. Shujun Fu
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  3. Lun-Quan Sun
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Correspondence to Lun-Quan Sun .

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  1. Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China

    Erwei Song

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Li, Z., Fu, S., Sun, LQ. (2016). Viral Noncoding RNAs in Cancer Biology. In: Song, E. (eds) The Long and Short Non-coding RNAs in Cancer Biology. Advances in Experimental Medicine and Biology, vol 927. Springer, Singapore. https://doi.org/10.1007/978-981-10-1498-7_14

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