Pathophysiology of Subarachnoid Hemorrhage

  • Sook Young Sim
  • Yong Sam Shin
Part of the Stroke Revisited book series (STROREV)


Spontaneous subarachnoid hemorrhage (SAH) is an important cause of stroke. It is associated with high mortality and morbidity. SAH has differing hemorrhagic patterns, clinical course, prognosis, and therapeutic method, depending on the cause of the bleeding. The most common etiology of SAH is a rupture of an aneurysm arising at the intracranial artery. This chapter describes the underlying pathogenesis of aneurysmal formation, growth, and rupture. Not only the initial hemorrhage but also the ways in which pathophysiological processes following aneurysmal SAH may influence the complicated clinical course of survivors. Furthermore, the chapter discusses updated pathophysiology of post-hemorrhagic phenomena, including aneurysmal rebleeding, hydrocephalus, early brain injury, delayed cerebral ischemia, and medical complications. Finally, non-aneurysmal SAH is rare but is associated with diverse etiologies; the chapter summarizes proposed mechanisms of bleeding and clinical characteristics of non-aneurysmal SAH.


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Copyright information

© Springer Science+Business Media Singapore 2018

Authors and Affiliations

  • Sook Young Sim
    • 1
  • Yong Sam Shin
    • 2
  1. 1.Department of NeurosurgeryCollege of Medicine, Seoul Paik Hospital, Inje UniversitySeoulSouth Korea
  2. 2.Department of NeurosurgeryCollege of Medicine, Seoul St. Mary’s Hospital, The Catholic University of KoreaSeoulSouth Korea

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