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New Strategy of Clinical Studies for Premature Babies with Ischemic Brain Damage

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Cell Therapy for Perinatal Brain Injury

Abstract

In Japan, we started autologous cord blood therapy for newborns with HIE in 2014 (described in Chap. 1). Another research group started autologous cord blood therapy for patients with cerebral palsy in 2017. However, cerebral palsy is induced in nearly twice as many premature babies with IVH and PVL as that by term newborns with HIE (Touyama et al. Brain Dev 38:792–799, 2016; Koterazawa et al. No to Hattatsu 48:14–19, 2016; Glinianaia et al. Dev Med Child Neurol 59:864–870, 2017). Therefore, we are now promoting a new clinical study protocol of cell therapy for premature newborns with PVL or IVH.

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Authors and Affiliations

  1. Department of Pediatrics, Yodogawa Christian Hospital, Higashiyodogawa-ku, 1-7-50, Osaka City, Japan

    Makoto Nabetani M.D., Ph.D.

  2. Department of Pediatrics, Osaka City University Graduate School of Medicine, Osaka-shi, Japan

    Haruo Shintaku M.D., Ph.D.

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  1. Makoto Nabetani M.D., Ph.D.
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Correspondence to Makoto Nabetani M.D., Ph.D. .

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Editors and Affiliations

  1. Department of Pediatrics, Osaka City University Graduate School of Medicine, Osaka, Japan

    Haruo Shintaku

  2. Department of Pediatrics, University of Tokyo, Tokyo, Japan

    Akira Oka

  3. Department of Pediatrics, Yodogawa Christian Hospital, Osaka, Japan

    Makoto Nabetani

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Nabetani, M., Shintaku, H. (2018). New Strategy of Clinical Studies for Premature Babies with Ischemic Brain Damage. In: Shintaku, H., Oka, A., Nabetani, M. (eds) Cell Therapy for Perinatal Brain Injury. Springer, Singapore. https://doi.org/10.1007/978-981-10-1412-3_2

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  • DOI: https://doi.org/10.1007/978-981-10-1412-3_2

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