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A New Prospective Cell Therapy for Neonatal Brain Injury

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Cell Therapy for Perinatal Brain Injury

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Abstract

Cerebral palsy is a lifelong neurological disorder, mainly caused by hypoxic-ischemic encephalopathy, hemorrhage, and periventricular leukomalacia occurring at delivery or perinatally. To prevent or reduce the neurogenic disabilities in cerebral palsy, therapies using hypothermia, autologous cord blood infusion, and recently, mesenchymal stromal cells (MSCs) have been applied. MSCs can be obtained from fetal appendages such as cord blood, umbilical cord, amnion, and placenta. In this chapter, the expected feasibility of such cell therapies for cerebral palsy is discussed.

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Authors and Affiliations

  1. Department of Cell Processing and Transfusion, Research Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

    Tokiko Nagamura-Inoue M.D., Ph.D.

Authors
  1. Tokiko Nagamura-Inoue M.D., Ph.D.
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Correspondence to Tokiko Nagamura-Inoue M.D., Ph.D. .

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Editors and Affiliations

  1. Department of Pediatrics, Osaka City University Graduate School of Medicine, Osaka, Japan

    Haruo Shintaku

  2. Department of Pediatrics, University of Tokyo, Tokyo, Japan

    Akira Oka

  3. Department of Pediatrics, Yodogawa Christian Hospital, Osaka, Japan

    Makoto Nabetani

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© 2018 Springer Nature Singapore Pte Ltd.

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Nagamura-Inoue, T. (2018). A New Prospective Cell Therapy for Neonatal Brain Injury. In: Shintaku, H., Oka, A., Nabetani, M. (eds) Cell Therapy for Perinatal Brain Injury. Springer, Singapore. https://doi.org/10.1007/978-981-10-1412-3_14

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  • DOI: https://doi.org/10.1007/978-981-10-1412-3_14

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-1411-6

  • Online ISBN: 978-981-10-1412-3

  • eBook Packages: MedicineMedicine (R0)

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