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Cushing’s Syndrome

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Evidence-Based Endocrine Surgery

Abstract

Cushing’s syndrome is a rare clinical entity resulting from pathologic hypercortisolemia [1]. Patients may present along a spectrum of severity from classical signs and symptoms of cortisol excess to subclinical or entirely asymptomatic disease [1–3]. The most common endogenous causes are ACTH-producing pituitary adenomas, cortisol-secreting adrenal adenomas, and ectopic ACTH-secreting tumors [4, 5]. Arriving at an accurate diagnosis of the underlying etiology and initiating appropriate treatment in a timely manner are essential to preventing morbidity and mortality [6, 7]. Diagnostic evaluation requires a systematic approach and significant expertise [2, 4]. Although surgery is often the primary treatment modality, multispecialty care is often necessary for optimal outcomes [8].

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Authors and Affiliations

  1. Capital Surgeons Group, Austin, Texas, USA

    Roy Lirov

  2. Division of Endocrine Surgery, Department of Surgery, Michigan Medicine, Ann Arbor, MI, USA

    Paul G. Gauger

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  1. Division of Endocrine Surgery, National University Hospital, Singapore, Singapore

    Rajeev Parameswaran

  2. Department of Endocrine Surgery, SGPGI Hospital, Lucknow, India

    Amit Agarwal

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Lirov, R., Gauger, P.G. (2018). Cushing’s Syndrome. In: Parameswaran, R., Agarwal, A. (eds) Evidence-Based Endocrine Surgery. Springer, Singapore. https://doi.org/10.1007/978-981-10-1124-5_26

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