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Perspectives in Translational Research in Life Sciences and Biomedicine pp 77–87Cite as

Dissecting Key Cellular Players Regulating Pathophysiology of Acute and Chronic Allergic Asthma

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Abstract

The Global Initiative in Asthma (2009) defines asthma as “a chronic inflammatory disorder of the airways in which many cells and cellular elements play a role. The chronic inflammation is associated with airway hyper-responsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness, and coughing, particularly at night or in the early morning. These episodes are usually associated with widespread, but variable, airflow obstruction within the lung that is often reversible either spontaneously or with treatment.” Over a past few decades, different researchers throughout the globe have involved themselves on the understanding of the pathophysiological basis of asthma at the cellular and molecular levels though the fundamental causes of the disease and the reasons for increased prevalence rates remain unclear.

Proposal for the translational research project and its relevance.

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Authors and Affiliations

  1. Department of Zoology, University of Calcutta, Kolkata, India

    Ena Ray Banerjee

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Correspondence to Ena Ray Banerjee .

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Ray Banerjee, E. (2016). Dissecting Key Cellular Players Regulating Pathophysiology of Acute and Chronic Allergic Asthma. In: Perspectives in Translational Research in Life Sciences and Biomedicine. Springer, Singapore. https://doi.org/10.1007/978-981-10-0989-1_5

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