Abstract
Man from the very beginning in his evolutionary history is found to be involved in the manipulation of the traits of the animals and plants according to his need or desire. Prior to the development of molecular genetics, the only way of studying the regulation and function of mammalian genes was through the observation of inherited characteristics or spontaneous mutations, and selective breeding was a common practice among farmers for the enhancement of chosen traits. As the revolution took place in applied molecular genetics, new techniques evolved to study gene expression. Recent development of transgenic organism is one of those techniques.
Transgenic organisms as a subset of genetically modified organisms (GMOs) are organisms which have inserted DNA of different species origin; the inserted DNA/gene is known as transgene. Transgene is introduced into the organism, using recombinant DNA technology, and it must be transmitted through the germline so that every cell, including germ cells, of the body contains the same modified genetic material. In this chapter, readers would understand the methods of generation of transgenic animals and plants and the factors which affect the expression of transgene.
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Gupta, V., Sengupta, M., Prakash, J., Tripathy, B.C. (2017). Transgenic Animals and Plants. In: Basic and Applied Aspects of Biotechnology. Springer, Singapore. https://doi.org/10.1007/978-981-10-0875-7_5
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DOI: https://doi.org/10.1007/978-981-10-0875-7_5
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