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Combination Therapy with Hyperthermia and Chemoradiotherapy: Oral Cancer

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Book cover Hyperthermic Oncology from Bench to Bedside

Abstract

The major prognostic factors for survival in patients with oral cavity cancer are local control, neck control, and distant metastasis. Oral cancer patients with advanced cervical lymph node metastases have poor prognosis. Hyperthermia has generally been used for management of cervical lymph node metastases that are accessible with a radiofrequency system using external application, and in combination with synergistic chemoradiotherapy. Thermochemoradiotherapy using retrograde superselective intra-arterial infusion is used in patients with advanced cervical lymph node metastases, and can be used to treat the primary lesion as well as cervical lymph node metastases.

In this chapter, the therapeutic results of retrograde superselective intra-arterial chemoradiotherapy and thermochemoradiotherapy for patients with advanced oral cancer and advanced cervical lymph node metastases are described.

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Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan

    Kenji Mitsudo & Iwai Tohnai

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  1. Kenji Mitsudo
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  2. Iwai Tohnai
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Correspondence to Kenji Mitsudo .

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Editors and Affiliations

  1. Kokura Lab, Health and Medical Sciences, Kyoto Gakuen University, Kyoto, Kyoto, Japan

    Satoshi Kokura

  2. Department of Inflammation and Immunolog, Kyoto Prefectural University of Medicine, Kyoto, Kyoto, Japan

    Toshikazu Yoshikawa

  3. Department of Radiation Oncology, Nara Medical University, Kashihara, Nara, Japan

    Takeo Ohnishi

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Mitsudo, K., Tohnai, I. (2016). Combination Therapy with Hyperthermia and Chemoradiotherapy: Oral Cancer. In: Kokura, S., Yoshikawa, T., Ohnishi, T. (eds) Hyperthermic Oncology from Bench to Bedside. Springer, Singapore. https://doi.org/10.1007/978-981-10-0719-4_16

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  • DOI: https://doi.org/10.1007/978-981-10-0719-4_16

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-0717-0

  • Online ISBN: 978-981-10-0719-4

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