Abstract
Non-covalent interactions are relatively weak and reversible which means that it is particularly difficult to identify trends and patterns and to establish a hierarchy of molecular-recognition efficiency in a competitive situation, but it is important to note that the seemingly simple act of molecular recognition is achieved by balancing a range of non-covalent forces, and the synthesis of more complex architectures requires a systematic and targeted application of hierarchical self-assembly. In this contribution we illustrate how robust and reliable supramolecular synthetic strategies can be translated into the deliberate design of molecular solids, notably co-crystals, with tunable or desired function. We will focus our attention on energetic materials, pharmaceutically active compounds, and cavitands for host-guest applications.
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Aakeröy, C.B., Sandhu, B. (2017). Solid Form Landscape and Design of Physical Properties. In: Roberts, K., Docherty, R., Tamura, R. (eds) Engineering Crystallography: From Molecule to Crystal to Functional Form. NATO Science for Peace and Security Series A: Chemistry and Biology. Springer, Dordrecht. https://doi.org/10.1007/978-94-024-1117-1_4
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DOI: https://doi.org/10.1007/978-94-024-1117-1_4
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