Abstract
Environmental prevention strategies include the development of suitable analytical protocols to assess health risk associated to exposure to drugs and fraudulently modified foods. Mass spectrometry (MS) is the analytical methodology of choice since it is based on the identification and assay of organic and inorganic components present, and eventually fraudulently added, to foods. An important achievement of the methodology is represented by the so-called ambient ionization approach that allows the direct evaluation of species present in fluids and/or solids without any previous chemical manipulation.
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References
Jakob A, Crawford EA, Gross JH (2016) Detection of Polydimethylsiloxanes transferred from silicone-coated parchment paper to baked goods using direct analysis in real time mass spectrometry. J Mass Spectrom 51:298–304
Cody RB, Laramée JA, Durst HD (2005) Versatile new ion source for the analysis of materials in open air under ambient conditions. Anal Chem 77:2297–2302
De Nino A, Di Donna L, Mazzotti F, Perri E, Raffaelli A, Sindona G, Urso E (2001) Quantitative determination of Oleuropein in organic olive oil by ESI-MS/MS and Isotope Dilution. In: Pfannhauser W, Fenwick GR, Khokar SR (eds) Biologically-active phytochemicals in food. Analysis, metabolism, bioavailability and function. The Royal Society of Chemistry, Cambridge, p 131
De Nino A, Di Donna L, Mazzotti F, Muzzalupo E, Perri E, Sindona G, Tagarelli A (2005) Absolute method for the assay of Oleuropein in olive oils by atmospheric pressure chemical ionization tandem mass spectrometry. Anal Chem 77(18):5961
Sindona G (2010) Chapter 11: A marker of quality of olive oils: the expression of Oleuropein. In: Preedy V, Watson R (eds) Olives and olive oil in health and disease prevention. Academic Press, London, pp 95–100
La Marca G (2014) Mass spectrometry in clinical chemistry: the case of newborn screening. J Pharm Biomed Anal 101:174–182
Mcgorrin RJ (2009) One hundred years of progress in food analysis. J Agric Food Chem 57:8076–8088
Lynch JM, Barbano DM (1999) Kjeldahl nitrogen analysis as a reference method for protein determination in dairy products. J AOAC Int 82:1389–1401
Wu Q, Fan KX, Sha W, Ruan HQ, Zeng R, Shieh CH (2009) Highly sensitive detection of melamine based on reversed phase liquid chromatography mass spectrometry. Chin Sci Bull 54:732–737
Di Donna L, Maiuolo L, Mazzotti F, De Luca D, Sindona G (2004) Assay of Sudan I contamination of foodstuff by atmospheric pressure chemical ionization tandem mass spectrometry and Isotope Dilution. Anal Chem 76:5104–5108
Di Donna L, De Nino A, Maiuolo L, Mazzotti F, Napoli A, Salerno R, Sindona G (2007) High-throughput mass spectrometry: the mechanism of sudan azo dye fragmentation by ESI tandem mass spectrometry and extensive deuterium labeling experiments. J Mass Spectrom 42:1057–1061
Mazzotti F, Di Donna L, Maiuolo L, Napoli A, Salerno R, Sajjad A, Sindona G (2008) Assay of the set of all Sudan Azodyes (I, II, III, IV, and Para-red) contaminating agents by liquid chromatography-tandem mass spectrometry and Isotope Dilution methodology. J Agric Food Chem 56:63–67
Taverna D, Di Donna L, Mazzotti F, Policicchio B, Sindona G (2013) High-throughput determination of Sudan Azo-dyes within powdered chili pepper by paper spray mass spectrometry. J Mass Spectrom 48:544–547
Liu J, Wnag H, Nanicke NE, Lin J-M, Cooks RG, Ouyang Z (2010) Development, characterization, and application of paper spray ionization. Anal Chem 82:2463–2471
Taverna D, Di Donna L, Mazzotti F, Tagarelli A, Napoli A, Furia E, Sindona G (2016) Rapid discrimination of bergamot essential oil by paper spray mass spectrometry and Chemometric analysis. J Mass Spectrom 51:761–767
Bradshaw R, Wolstenholme R, Blackledge RD, Clench MR, Ferguson LS, Francese S (2011) A novel matrix-assisted laser Desorption/ionization mass spectrometry imaging based methodology for the identification of sexual assault suspects. Rapid Commun Mass Spectrom 25:415–422
Mirabelli MF, Ifa DR, Sindona G, Tagarelli A (2015) Analysis of sexual assault evidence: statistical classification of condoms by ambient mass spectrometry. J Mass Spectrom 50:749–755
Mulligan CC, Talaty N, Cooks RG (2006) Desorption electrospray ionization with a portable mass spectrometer: in situ analysis of ambient surfaces. Chem Commun 16:1709–1711
Harper JD, Charipar NA, Mulligan CC, Zhang X, Cooks RG, Ouyang Z (2008) Low-temperature plasma probe for ambient desorption ionization. Anal Chem 80:9097–9104
Garcıa-Reyes JF, Mazzotti F, Harper JD, Charipar NA, Oradu S, Ouyang Z, Sindona G, Cooks RG (2009) Direct olive oil analysis by Low-Temperature Plasma (LTP) ambient ionization mass spectrometry. Rapid Commun Mass Spectrom 23:3057–3062
Taverna D, Di Donna L, Bartella L, Napoli A, Sindona G, Mazzotti F (2016) Fast analysis of caffeine in beverages and drugs by paper spray tandem mass spectrometry. Anal Bioanal Chem 408:3783–3787
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Sindona, G. (2017). Advanced Mass Spectrometric Methodologies in the Evaluation of Health Risk Assessment Associated to Exposure to Drugs and Fraudulenty Modified Foods. In: Banoub, J., Caprioli, R. (eds) Molecular Technologies for Detection of Chemical and Biological Agents. NATO Science for Peace and Security Series A: Chemistry and Biology. Springer, Dordrecht. https://doi.org/10.1007/978-94-024-1113-3_12
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DOI: https://doi.org/10.1007/978-94-024-1113-3_12
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